Evidence map›Paper›PMID 34291178›Full record

ArticleCommunications chemistry2018

Performing radiosynthesis in microvolumes to maximize molar activity of tracers for positron emission tomography.

Maxim E Sergeev, Mark Lazari, Federica Morgia, Jeffrey Collins, Muhammad Rashed Javed, Olga Sergeeva, Jason Jones, Michael E Phelps, Jason T Lee, Pei Yuin Keng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Detrimental impact of aqueous mobile phases on 18F-labelled radiopharmaceutical analysisAnalytical methods : advancing methods and applications · 2023
    Article
  9. High molar activity [EJNMMI radiopharmacy and chemistry · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Journal of organic chemistry · 2021
    Article
  15. Review
  16. Sulfur [Journal of the American Chemical Society · 2021
    Article
  17. Optimization of Radiochemical Reactions using Droplet Arrays.Journal of visualized experiments : JoVE · 2021
    Article
  18. Synthesis of [ACS chemical neuroscience · 2021
    Article
  19. Article
  20. Nature catalysis · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maxim E SergeevCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Mark LazariCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Federica MorgiaCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Jeffrey CollinsCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Muhammad Rashed JavedCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Olga SergeevaCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Jason JonesPhysics and Biology in Medicine Interdepartmental Graduate Program, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Michael E PhelpsCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Jason T LeeCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
Pei Yuin KengCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.
R Michael van DamCrump Institute for Molecular Imaging, University of California, Los Angeles (UCLA), 570 Westwood Plaza, Los Angeles, CA, USA, 90095.

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
UCLA SPORE IN PROSTATE CANCERP50CA092131 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI REITER, ROBERT E · 2002 to 2023
$42.6M
Transductionally Redirected /Transcriptionally RestricteP50CA086306 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HERSCHMAN, HARVEY R. · 2000 to 2014
$29.0M
UCLA Institute for Molecular Medicine (IMED) CoreU54CA151819 · NCI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HEATH, JAMES R. · 2010 to 2014
$12.1M
Research Training in Biomedical PhysicsT32EB002101 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Michael F McNitt-Gray · 2003 to 2026
$5.3M
Automated microfluidic production of high specific activity PET tracers to enable routine CNS imagingR21AG049918 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DAM, ROBERT MICHAEL · 2015 to 2017
$693k
Microliter radiosynthesizer for producing high specific activity PET ligandsR21EB015540 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DAM, ROBERT MICHAEL · 2012 to 2013
$405k
NCI NIH HHS P30 CA016042NCI NIH HHS P50 CA086306NCI NIH HHS P50 CA092131NCI NIH HHS U54 CA151819NIA NIH HHS R21 AG049918NIBIB NIH HHS R21 EB015540NIBIB NIH HHS T32 EB002101
6 · The paper itself

Abstract

Positron emission tomography (PET) is a molecular diagnostic imaging technology to quantitatively visualize biological processes

Identifiers

PMID34291178
PMCPMC8291036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.