Evidence map›Paper›PMID 34291130›Full record

ReviewGenes & diseases2021

Breast and gut microbiome in health and cancer.

Jilei Zhang, Yinglin Xia, Jun Sun

Open access · diamondAbstract readReview
In one paragraph

Review in Genes & diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 120 citations in OpenAlex.

  1. Review
  2. Review
  3. The Role of Selected Bacteria in Breast Cancer Initiation and Development.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. iScience · 2025
    Article
  12. Article
  13. Article
  14. Dysbiosis and extraintestinal cancers.Journal of experimental & clinical cancer research : CR · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Case Report:Frontiers in medicine · 2025
    Article
  19. Review
  20. IntratumoralInternational journal of biological sciences · 2025
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jilei ZhangDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
Yinglin XiaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
Jun SunDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
University of Illinois Chicago · US

Funding

How Vitamin D Receptor Influences Intestinal BarriersR01DK114126 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2018 to 2026
$3.0M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK105118 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUN, JUN · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK105118NIDDK NIH HHS R01 DK114126
6 · The paper itself

Abstract

The microbiota plays essential roles in health and disease, in both the intestine and the extra-intestine. Dysbiosis of the gut microbiota causes dysfunction in the intestine, which leads to inflammatory, immune, and infectious diseases. Dysbiosis is also associated with diseases beyond the intestine via microbial translocation or metabolisms. The

Indexed as

Breast cancerBreast microbiomeDysbiosisInflammationMetaboliteMicronutritionProbioticsTransfer RNAs

Identifiers

PMID34291130
PMCPMC8278537
OpenAlexW3074049511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.