ArticleFrontiers in oncology2021
The Treatment Outcomes of Olfactory Neuroblastoma Patients With Frontal Lobe Invasion.
Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Assessing Olfactory Bulb Infiltration and Morphological Changes in Olfactory Neuroblastoma Using Magnetic Resonance Imaging.Journal of neurological surgery. Part B, Skull base · 2026Article
- Induction Chemotherapy for Sinonasal Tumors in Patients Presenting with Brain Invasion and/or Neurological Deficits.Journal of neurological surgery. Part B, Skull base · 2024Article
- Upright proton therapy for esthesioneuroblastoma: a single-institution experience.Frontiers in oncology · 2024Article
- Treatment outcomes and prognostic factors of esthesioneuroblastoma-a retrospective study from South India.Ecancermedicalscience · 2023Article
- The Selective Role of Open and Endoscopic Approaches for Sinonasal Malignant Tumours.Advances in therapy · 2022Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundTo investigate whether frontal lobe invasion (FLI) was an unfavorable prognostic factor in patients with olfactory neuroblastoma (ONB), and to explore the optimal treatment strategy for ONB patients with FLI.
methodsSome 37 patients with FLI were retrospectively studied, and 74 well-matched patients without FLI were enrolled as the control group. The long-term survivals were compared between the two groups.
resultsNo significant differences were found between the two groups in overall survival (OS), progression-free survival (PFS), locoregional failure-free survival (LRFS), and distant metastasis-free survival (DMFS) (all p >0.05). Multivariate analyses showed that FLI wasn't an independent predictor for OS (HR = 1.100, 95% CI = 0.437-2.772, p = 0.840). Among the 37 patients with FLI, patients who received surgery combined with chemo-/radiotherapy showed better OS (89.4%
conclusionsFLI wasn't a poor prognostic factor for ONB patients. Endoscopic resection combined with radiotherapy was an effective therapeutic method for ONB patients with FLI.
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