Evidence map›Paper›PMID 34290966›Full record

ArticleAvicenna journal of phytomedicine

Hypoglycemic, hypolipidemic and hepato-protective effect of bee bread in streptozotocin-induced diabetic rats.

Meryem Bakour, Nawal El Menyiy, Asmae El Ghouizi, Badiaa Lyoussi

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Attenuation of diabetes linked testicular co-morbidity byAvicenna journal of phytomedicine · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. LC-MS-based metabolite profiling of aqueous extract ofIranian journal of basic medical sciences · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Meryem BakourLaboratory of Natural Substances, Pharmacology, Environment, Modeling, Health and Quality of life (SNAMOPEQ), Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Nawal El MenyiyLaboratory of Natural Substances, Pharmacology, Environment, Modeling, Health and Quality of life (SNAMOPEQ), Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Asmae El GhouiziLaboratory of Natural Substances, Pharmacology, Environment, Modeling, Health and Quality of life (SNAMOPEQ), Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Badiaa LyoussiLaboratory of Natural Substances, Pharmacology, Environment, Modeling, Health and Quality of life (SNAMOPEQ), Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Sidi Mohamed Ben Abdellah University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to shed a new light on pharmacological effects of bee bread as a product of the hive through examination of the effect of itsethyl acetate extract onhyperglycemia, dyslipidemia, and liver dysfunction induced by streptozotocin. MATERIALS AND

methodsThe bee bread ethyl acetate extract was analyzed for total phenolics, flavonoids, and the antioxidant activities using total antioxidant capacity, 2, 2- diphenyl-1-picrylhydrazyl (DPPH), 2, 2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS), and reducing power assays.

resultsThe results indicate that bee bread ethyl acetate extract has a high content of phenolics and flavonoids and a strong antioxidant activity. Glycemia, lipid profile and hepatic enzymes were modified in diabetic rats. These modifications were ameliorated after the treatment withbee bread extract which was more potent than glibenclamide.

conclusionIn summary, ethyl acetate extract of bee bread possesses effective glycemia lowering effects and representsa natural source of new bioactive molecules for future therapy of hyperglycemia, hyperlipidemia and liver dysfunction.

Indexed as

Bee breadDiabetesHyperlipidemiaLiver

Identifiers

PMID34290966
PMCPMC8264221
OpenAlexW3143578627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.