ArticleApplied sciences (Basel, Switzerland)2021
Accurate and Robust Alignment of Differently Stained Histologic Images Based on Greedy Diffeomorphic Registration.
Article in Applied sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Discriminating inflammation from malignancy with short-dynamic patlak parametric 18 F-FDG PET/CT.European journal of nuclear medicine and molecular imaging · 2026Article
- Subtype-Specific Metabolic Patterns in Staging Breast Cancer: Insights from Conventional and Parametric PET Radiomics.Cancers · 2026Article
- A high-precision hierarchical registration approach for stain- and scanner-independent colocalization on whole slide images in histopathology.Health information science and systems · 2025Article
- Automatic Segmentation of Medial Temporal Lobe Subregions in Multi-Scanner, Multi-Modality Magnetic Resonance Imaging of Variable Quality.Hippocampus · 2025Article
- Automatic segmentation of medial temporal lobe subregions in multi-scanner, multi-modality magnetic resonance imaging of variable quality.bioRxiv : the preprint server for biology · 2025Article
- Spatial integration of multi-omics data from serial sections using the novel Multi-Omics Imaging Integration Toolset.GigaScience · 2025Article
- Publicly available datasets of breast histopathology H&E whole-slide images: A scoping review.Journal of pathology informatics · 2024Article
- Optimization, characterization and biosafety of carotenoids produced from whey using Micrococcus luteus.BMC biotechnology · 2024Article
- Computational methods and biomarker discovery strategies for spatial proteomics: a review in immuno-oncology.Briefings in bioinformatics · 2024Review
- Extracting value from total-body PET/CT image data - the emerging role of artificial intelligence.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Review
- Comparison of consecutive and restained sections for image registration in histopathology.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Virtual alignment of pathology image series for multi-gigapixel whole slide images.Nature communications · 2023Article
- Fully Automated, Fast Motion Correction of Dynamic Whole-Body and Total-Body PET/CT Imaging Studies.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- Current Approaches for Image Fusion of Histological Data with Computed Tomography and Magnetic Resonance Imaging.Radiology research and practice · 2022Review
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Authors and funding
6 authors.
Funding
Abstract
Histopathologic assessment routinely provides rich microscopic information about tissue structure and disease process. However, the sections used are very thin, and essentially capture only 2D representations of a certain tissue sample. Accurate and robust alignment of sequentially cut 2D slices should contribute to more comprehensive assessment accounting for surrounding 3D information. Towards this end, we here propose a two-step diffeomorphic registration approach that aligns differently stained histology slides to each other, starting with an initial affine step followed by estimating a deformation field. It was quantitatively evaluated on ample (
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