Evidence map›Paper›PMID 34290864›Full record

ArticleJournal of nutritional science2021

A high-protein diet containing inulin/oligofructose supports body weight gain associated with lower energy expenditure and carbohydrate oxidation, and alters faecal microbiota in C57BL/6 mice.

Franziska Koch, Michael Derno, Martina Langhammer, Armin Tuchscherer, Harald M Hammon, Manfred Mielenz, Cornelia C Metges, Björn Kuhla

Open access · goldAbstract read
In one paragraph

Article in Journal of nutritional science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. The Effect of a Diet Enriched withCurrent issues in molecular biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Franziska KochInstitute of Nutritional Physiology "Oskar Kellner", Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Michael DernoInstitute of Nutritional Physiology "Oskar Kellner", Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Martina LanghammerInstitute of Genetics and Biometry, Service Group Lab Animal Facility, Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Armin TuchschererInstitute of Genetics and Biometry, Livestock Genetics and Breeding Unit, Institute for Farm Animal Biology (FBN), Wilhelm-Stahl Allee 2, 18196 Dummerstorf, Germany.
Harald M HammonInstitute of Nutritional Physiology "Oskar Kellner", Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Manfred MielenzInstitute of Nutritional Physiology "Oskar Kellner", Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Cornelia C MetgesInstitute of Nutritional Physiology "Oskar Kellner", Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Björn KuhlaInstitute of Nutritional Physiology "Oskar Kellner", Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Research Institute for Farm Animal Biology (FBN) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prebiotic supplements and high-protein (HP) diets reduce body weight and modulate intestinal microbiota. Our aim was to elucidate the combined effect of an inulin/oligofructose (FOS) and HP diet on body weight gain, energy metabolism and faecal microbiota. Forty male C57BL/6NCrl mice were fed a control (C) diet for 2 weeks and allocated to a C or HP (40 % protein) diet including no or 10 % inulin/FOS (C + I and HP + I) for 4 weeks. Inulin/FOS was added in place of starch and cellulose. Body weight, food intake, faecal energy and nitrogen were determined. Indirect calorimetry and faecal microbiota analysis were performed after 3 weeks on diets. Body weight gain of HP-fed mice was 36 % lower than HP + I- and C-fed mice (

Indexed as

Diet, High-ProteinMicrobiotaWeight GainAnimalsBody WeightCarbohydrate MetabolismCarbohydratesEnergy MetabolismFecesInulinMaleMiceMice, Inbred C57BLNitrogenOligosaccharidesCarbohydratesInulinNitrogenoligofructoseOligosaccharidesC, controlCOX, carbohydrate oxidationEB, energy balanceEnergy expenditureFOS, oligofructoseFOX, fat oxidationHigh-protein dietHP, high protein+I, inulin/oligofructoseInulinMicrobiotaNitrogen excretionRQ, respiratory quotientTEE, total energy expenditure

Identifiers

PMID34290864
PMCPMC8278163
OpenAlexW3179007756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.