Evidence map›Paper›PMID 34290536›Full record

ArticleNature and science of sleep2021

The Effects of Altitude-related Hypoxia Exposure on the Multiscale Dynamics of Blood Pressure Fluctuation During Sleep: The Observation from a Pilot Study.

Qian Li, Zhenxiang Guo, Fuzheng Liu, Ye Liu, Dapeng Bao, Junhong Zhou

Open access · goldAbstract read
In one paragraph

Article in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Qian Li *Sports Coaching College, Beijing Sport University, Beijing, People's Republic of China.
Zhenxiang Guo *Sports Coaching College, Beijing Sport University, Beijing, People's Republic of China.
Fuzheng LiuSchool of Medical Humanities, Capital Medical University, Beijing, People's Republic of China.
Ye LiuNational Team Performance Training Center, National Sports Training Center, General Administration of Sport of China, Beijing, People's Republic of China.
Dapeng BaoChina Institute of Sport and Health Science, Beijing Sport University, Beijing, People's Republic of China.
Junhong ZhouHebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research, Harvard Medical School, Boston, MA, 02131, USA.ORCID 0000-0002-7931-7646
Beijing Sport University · CNCapital Medical University · CNGeneral Administration of Sport of China · CNHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose exposure to hypoxia in high altitudes severely impairs the sleep quality and the related cardiovascular regulation, including the blood pressure (BP) regulation. BP regulation depends upon the continuous interaction of components over multiple temporal scales. As such, the dynamics of BP fluctuation are complex, and BP complexity has been linked to several pathological events. However, the effects of the exposure to hypoxia on BP complexity during sleep remain unknown.

methodsTwenty-five younger men naïve to high-altitude sleep (apnea severity as assessed by hypoxia apnea index (AHI): normal=8; moderate=9; severe=8) completed one nocturnal sleep under each of the three altitudes: 0 (ie, baseline), 2000, and 4000 m. The sleep characteristics and oxygen saturation (ie, SpO

resultsCompared to 0-m condition, SBP (

conclusionThese results suggested that the characterization of BP complexity may provide novel insights into the underlying mechanisms through which the exposure to hypoxia affects cardiovascular health during sleep, as well as sleep quality. This BP complexity may serve as a novel marker to help the management of cardiovascular health and sleep quality in high-altitude living.

Indexed as

beat-to-beat blood pressurehigh altitudemultiscale entropysleep quality

Identifiers

PMID34290536
PMCPMC8289331
OpenAlexW3180670613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.