Evidence map›Paper›PMID 34290469›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2018

Advanced Image Registration and Reconstruction using the O-Arm System: Dose Reduction, Image Quality, and Guidance using Known-Component Models.

A Uneri, X Zhang, J W Stayman, P Helm, G M Osgood, N Theodore, J H Siewerdsen

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. 3D-2D Image Registration in Virtual Long-Film Imaging: Application to Spinal Deformity Correction.Proceedings of SPIE--the International Society for Optical Engineering · 2019
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

A UneriDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD.
X ZhangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD.
J W StaymanDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD.
P HelmMedtronic Inc., Littleton, MA.
G M OsgoodDepartment of Orthopaedic Surgery, Johns Hopkins Medical Institute, Baltimore, MD.
N TheodoreDepartment of Neurosurgery, Johns Hopkins Medical Institute, Baltimore, MD.
J H SiewerdsenDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD.
Medtronic (United States) · USJohns Hopkins University · US

Funding

Intraoperative Imaging for Guidance, Patient Safety, and OR Quality AssuranceR01EB017226 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SIEWERDSEN, JEFFREY H · 2014 to 2017
$2.1M
Training In Orthopaedic Team ScienceT32AR067708 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI JONES, LYNNE C., SHAFIQ, BABAR · 2015 to 2024
$2.0M
NIAMS NIH HHS T32 AR067708NIBIB NIH HHS R01 EB017226
6 · The paper itself

Abstract

purposeModel-based image registration and reconstruction offer strong potential for improved safety and precision in image-guided interventions. Advantages include reduced radiation dose, improved soft-tissue visibility (detection of complications), and accurate guidance with/without a dedicated navigation system. This work reports the development and performance of such methods on an O-arm system for intraoperative imaging and translates them to first clinical studies.

methodsTwo novel methodologies predicate the work: (1) Known-Component Registration (KC-Reg) for 3D localization of the patient and interventional devices from 2D radiographs; and (2) Penalized-Likelihood reconstruction (PLH) for improved 3D image quality and dose reduction. A thorough assessment of geometric stability, dosimetry, and image quality was performed to define algorithm parameters for imaging and guidance protocols. Laboratory studies included: evaluation of KC-Reg in localization of spine screws delivered in cadaver; and PLH performance in contrast, noise, and resolution in phantoms/cadaver compared to filtered backprojection (FBP).

resultsKC-Reg was shown to successfully register screw implants within ~1 mm based on as few as 3 radiographs. PLH was shown to improve soft-tissue visibility (61% improvement in CNR) compared to FBP at matched resolution. Cadaver studies verified the selection of algorithm parameters and the methods were successfully translated to clinical studies under an IRB protocol.

conclusionsModel-based registration and reconstruction approaches were shown to reduce dose and provide improved visualization of anatomy and surgical instrumentation. Immediate future work will focus on further integration of KC-Reg and PLH for Known-Component Reconstruction (KC-Recon) to provide high-quality intraoperative imaging in the presence of dense instrumentation.

Indexed as

3D-2D image registrationimage-guided surgeryIntraoperative imagingmodel-based image reconstruction

Identifiers

PMID34290469
PMCPMC8292104
OpenAlexW2791753903

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.