ArticleSynthesis2020
Rhodium(III)-Catalyzed Three-Component 1,2-Diamination of Unactivated Terminal Alkenes.
Article in Synthesis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- The Duality of Dioxolanyl Radicals towards C-C Bond Construction.Synlett : accounts and rapid communications in synthetic organic chemistry · 2025Article
- Unified Hydrogen Atom Transfer Approach To Construct Vicinal Functionality.Organic letters · 2025Article
- [3 + 2] Cycloadditions of Tertiary AmineOrganic letters · 2023Article
- The advent of electrophilic hydroxylamine-derived reagents for the direct preparation of unprotected amines.Chemical communications (Cambridge, England) · 2022Review
- Aziridination Reactivity of a Manganese(II) Complex with a Bulky Chelating Bis(Alkoxide) Ligand.Molecules (Basel, Switzerland) · 2022Article
- Rh(III)-catalyzed Intra- and Intermolecular 3,4-Difunctionalization of 1,3-DienesACS catalysis · 2022Article
- Rh(III)-Catalyzed Three-ComponentACS catalysis · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
We report a three-component diamination of simple unactivated alkenes using an electrophilic nitrene source and amine nucleophiles. The reaction provides rapid access to 1,2-vicinal diamines from terminal alkenes through a one-pot protocol. The transformation proceeds smoothly with excellent tolerance for a broad array of primary and secondary amines, affording the desired product with good yield and regioselectivity. The mechanism is proposed to proceed through a Rh(III)-catalyzed aziridination of alkenes with subsequent ring opening by primary or secondary amines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.