ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Process variations between Swiss units treating neonates with hypoxic-ischemic encephalopathy and their effect on short-term outcome.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Neonatal encephalopathy mortality rate in Aotearoa, New Zealand: review of national data 2010-2020.BMJ paediatrics open · 2026Article
- Risk of moderate or severe hypoxic ischemic encephalopathy does not correlate with prenatally known risk factors.Zeitschrift fur Geburtshilfe und Neonatologie · 2025Article
- Regional variability in therapeutic hypothermia eligibility criteria for neonatal hypoxic-ischemic encephalopathy.Pediatric research · 2024Review
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare therapeutic hypothermia (TH) treatment of term and near-term neonates with hypoxic-ischemic encephalopathy (HIE) between neonatal units. STUDY
designPopulation-based, retrospective analysis of TH initiation and maintenance, and of diagnostic imaging. The comparison between units was based on crude data analysis, indirect standardization, and adjusted logistic regression.
resultsTH was provided to 570 neonates with HIE between 2011 and 2018 in 10 Swiss units. We excluded 121 off-protocol cooled neonates to avoid selection bias. Of the remaining 449 neonates, the outcome was favorable to international benchmarks, but there were large unit-to-unit variations in baseline perinatal data and TH management. A total of 5% neonates did not reach target temperature within 7 h (3-10% between units), and 29% experienced over- or undercooling (0-38%).
conclusionAlthough the neonates had favorable short-term outcomes, areas for improvement remain for Swiss units in both process and outcome measures.
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