ArticleScientific reports2021
Male sex is not an independent risk factor for recurrence of differentiated thyroid cancer: a propensity score-matching study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- 2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer.Thyroid : official journal of the American Thyroid Association · 2025Guideline
- Editorial Comment: Sex as a Prognostic Factor in Follicular Thyroid Carcinoma: An Answer That Depends on Age.Annals of surgical oncology · 2026Article
- Sex and Mortality Among Patients with Papillary Thyroid Cancer.JAMA network open · 2026Article
- Article
- Personalized risk prediction of lateral lymph node metastasis in male papillary thyroid cancer: a sex-specific model leveraging central lymph node ratio.Future oncology (London, England) · 2025Article
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- Article
- Global, regional, and national burden of thyroid cancer in women of child-bearing age, 1990 to 2021 and predictions to 2035: An analysis of the global burden of disease study 2021.Frontiers in endocrinology · 2025Article
- PKCα Activation via the Thyroid Hormone Membrane Receptor Is Key to Thyroid Cancer Growth.International journal of molecular sciences · 2024Article
- UnexpectedAmerican journal of nuclear medicine and molecular imaging · 2024Article
- Article
- Impact of microscopic extrathyroidal extension on differentiated thyroid cancer post-surgical risk of recurrence: a retrospective analysis.Journal of endocrinological investigation · 2023Article
- Risk factors for recurrent disease in small papillary thyroid cancers - a Swedish register-based study.Langenbeck's archives of surgery · 2023Article
- Extrathyroidal extension and cervical node infiltration are associated with recurrences and shorter recurrence-free survival in differentiated thyroid cancer: a cohort study.Thyroid research · 2022Article
- Predictors of Recurrence in Patients with Papillary Thyroid Carcinoma: Does Male Sex Matter?Cancers · 2022Article
- Feasibility of Apatinib in Radioiodine-Refractory Differentiated Thyroid Carcinoma.Frontiers in endocrinology · 2022Article
- A Prognostic Model of Differentiated Thyroid Cancer Based on Up-Regulated Glycolysis-Related Genes.Frontiers in endocrinology · 2022Article
- Prognostic factors in patients with persistent/recurrent differentiated thyroid carcinoma after comprehensive treatmentZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021Article
- Papillary Thyroid Cancer Prognosis: An Evolving Field.Cancers · 2021Review
- EFFICACY AND PROGNOSIS IN PATIENTS WITH PAPILLARY THYROID CANCER WITH POSTOPERATIVE PREABLATIVE STIMULATED THYROGLOBULIN ABOVE 10 NG/ML AFTER INITIAL THERAPY WITH RADIOIODINE.Acta endocrinologica (Bucharest, Romania : 2005)Article
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5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Male patients have a significantly higher prevalence of advanced-stage thyroid cancer. However, sex differences in the risk of differentiated thyroid carcinoma (DTC) recurrence have not been fully elucidated. Therefore, the present study aimed to investigate male sex as a prognostic factor for DTC. We assessed 5566 patients with DTC who underwent thyroid surgery between January 2009 and December 2015 at Seoul St. Mary's Hospital (Seoul, Korea). Clinicopathological characteristics and long-term oncologic outcomes between female and male patients with DTC were compared using propensity score matching to reduce selection bias. The mean follow-up duration was 99.9 ± 18.7 months. The recurrence rate was significantly higher in male patients than female patients before matching (3.3% vs. 2.2%, p = 0.030), and there was no significant difference in recurrence rates between the matched groups after matching (3.0% vs. 2.5%, p = 0.591). Based on Kaplan-Meier analysis, the two groups did not significantly differ in disease-free survival after matching. Multivariate analysis revealed that male sex was not an independent prognostic factor of DTC recurrence. Male sex did not have a significant effect on DTC recurrence. Further studies with larger cohorts are required to validate the findings of this study.
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