Evidence map›Paper›PMID 34290008›Full record

ArticleBMJ case reports2021

Colchicine-induced rhabdomyolysis: a review of 83 cases.

Mohammad Abudalou, Ahmed S Mohamed, Eduardo A Vega, Ali Al Sbihi

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mohammad AbudalouMedicine, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0002-3137-377X
Ahmed S MohamedMedicine, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.
Eduardo A VegaSurgery, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0002-4643-0634
Ali Al SbihiInternal Medicine, Wayne State University, Detroit, Michigan, USA aalsbihi@dmc.org.ORCID http://orcid.org/0000-0002-0685-8652
Tufts University · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 74-year-old man with medical history significant for atrial fibrillation, hyperlipidaemia and coronary artery disease on atorvastatin presented to the emergency department with profound weakness. The patient reports he first noticed his weakness 4 weeks after starting colchicine, prescribed for recurrent pericarditis with pericardial effusion, a complication following recent coronary artery bypass grafting. The patient was also on prednisone therapy for presumed post-pericardiotomy syndrome. The weakness involved all four limbs but was more notable in the lower extremities, with preserved sensation and tenderness to palpation. Labs showed an elevated creatinine phosphokinase and serum creatinine consistent with rhabdomyolysis. Discontinuation of the offending medications, including colchicine and atorvastatin, as well as intravenous fluid resuscitation with physical rehabilitation, led to improvement in the patient's symptoms. He was eventually discharged to a rehabilitation facility to continue physical therapy.

Indexed as

Pericardial EffusionRhabdomyolysisAgedAtorvastatinColchicineCoronary Artery BypassHumansMaleAtorvastatinColchicinecardiovascular medicinedrug interactionsdrugs and medicinesunwanted effects / adverse reactions

Identifiers

PMID34290008
PMCPMC8296791
OpenAlexW3185426087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.