Evidence map›Paper›PMID 34289896›Full record

ArticleAsthma research and practice2021

Positive change in asthma control using therapeutic patient education in severe uncontrolled asthma: a one-year prospective study.

Xiaoxian Zhang, Zhengdao Lai, Rihuang Qiu, E Guo, Jing Li, Qingling Zhang, Naijian Li

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asthma research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06201728 (The Role of Asthma Flare-up Clinic in Improving Management and Outcomes of Asthma), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06201728 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

The Role of Asthma Flare-up Clinic in Improving Management and Outcomes of Asthma

TypeinterventionalSponsorTel-Aviv Sourasky Medical CenterRan2024 to 2026Enrolled230ConditionsAsthma, Asthma AttackArmsFollow-up in a flare-up clinic
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Xiaoxian Zhang *Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, 151 Yan Jiang Rd, 510000, Guangzhou, P.R. China.
Zhengdao Lai *Department of Pulmonary and Critical Care Medicine, Dongguan People's Hospital, 523000, Dongguan, P.R. China.
Rihuang QiuDepartment of Respiratory Medicine, The Affiliated Ganzhou Hospital of Nanchang University, 341000, Ganzhou, P.R. China.
E GuoXiangyang Central Hospital, Hubei University of Arts and Science, 441000, Xiangyang, P.R. China.
Jing LiDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, 151 Yan Jiang Rd, 510000, Guangzhou, P.R. China.
Qingling ZhangDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, 151 Yan Jiang Rd, 510000, Guangzhou, P.R. China.
Naijian LiDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, 151 Yan Jiang Rd, 510000, Guangzhou, P.R. China. naijian@126.com.
State Key Laboratory of Respiratory Disease · CNDongguan People’s Hospital · CNGanzhou People's Hospital · CNGuangzhou Medical University · CNHubei University of Arts and Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere asthma is difficult to control. Therapeutic patient education enables patients to better understand their disease and cope with treatment, but the effect of therapeutic patient education in severe uncontrolled asthma is unclear. We evaluated whether therapeutic patient education is effective in improving asthma control and decreasing the frequency of exacerbations in severe uncontrolled asthma.

methodsThis was a prospective, observational, and self-controlled study that enrolled 40 subjects with severe uncontrolled asthma. Patients were seen at a clinic four times (on day 1 and after 3, 6, and 12 months). After baseline data collection, the subjects completed a therapeutic patient education program and were also followed-up via telephone after 1, 2, 4, 5, 7, 8, 9, 10, and 11 months to monitor asthma medication adherence and collect asthma-related information.

resultsWithin the 1-year study period, a total of 23 exacerbations were recorded in 14 patients, seven of whom required emergency treatment and two of whom were hospitalized. Twelve months after the standardized therapeutic patient education program, pulmonary function and fractional exhaled nitric oxide levels improved significantly in all 40 patients. Moreover, the scores from three standardized asthma questionnaires and indices suggested improved quality of life in these patients with severe uncontrolled asthma. Serum levels of biomarkers reflecting asthma immune responses did not change between baseline and the 1-year follow-up time point.

conclusionsTherapeutic patient education is effective in improving asthma control and decreasing exacerbations in patients with severe uncontrolled asthma.

Indexed as

Asthma controlSevere uncontrolled asthmaTherapeutic patient education

Identifiers

PMID34289896
PMCPMC8293484
OpenAlexW3185326407

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.