Evidence map›Paper›PMID 34289879›Full record

ArticleTrials2021

Community-based intervention for prevention and management of chronic obstructive pulmonary disease in Nepal (COBIN-P trial): study protocol for a cluster-randomized controlled trial.

Tara Ballav Adhikari, Dinesh Neupane, Arjun Karki, Arne Drews, Brendan Cooper, Marieann Högman, Torben Sigsgaard, Per Kallestrup

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03797768 (Protocol for Community-based Management of Chronic Obstructive Pulmonary Disease in Nepal), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03797768 naunknown statusnot on this map

Protocol for Community-based Management of Chronic Obstructive Pulmonary Disease in Nepal: a Community-based Cluster Randomized Controlled Trial

TypeinterventionalSponsorUniversity of AarhusRan2019 to 2021Enrolled1,438ConditionsChronic Obstructive Pulmonary DiseaseArmsBehavioural-FCHV Visit
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 6 countries.

Tara Ballav AdhikariDepartment of Public Health, Section for Global Health, Aarhus University, Aarhus, Denmark. tba@ph.au.dk.ORCID http://orcid.org/0000-0002-7654-5483
Dinesh NeupaneCOBIN Project, Nepal Development Society, Bharatpur, Chitwan, Nepal.
Arjun KarkiDepartment of Pulmonary, Critical Care and Sleep Medicine, HAMS Hospital, Kathmandu, Nepal.
Arne DrewsNepalmed, Leipzig, Germany.
Brendan CooperLung Function and Sleep, University Hospitals Birmingham, Birmingham, UK.
Marieann HögmanDepartment of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
Torben SigsgaardDepartment of Public Health, Section for Environment, Occupation & Health, Aarhus University, Aarhus, Denmark.
Per KallestrupDepartment of Public Health, Section for Global Health, Aarhus University, Aarhus, Denmark.
Aarhus University · DKCivil Service Hospital · NPDJO Global (Germany) · DEJohns Hopkins University · USNIHR Surgical Reconstruction and Microbiology Research Centre · GBUppsala University · SE

Funding

This study received travel funding for Tara Ballav Adhikari from Aarhus University and partial support on buying spirometry from Nepalmed NA
6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide and the commonest of non-communicable diseases (NCDs) in Nepal. Risk factors like indoor and outdoor air pollution, a high prevalence of smoking, and the lack of awareness of COPD make it a serious public health concern. However, no attempt has been made in Nepal to estimate its burden and address the disease at the community level.

methodThis study aims to evaluate the effect of a community-based health educational intervention administered by Female Community Health Volunteers (FCHVs) on the prevention and management of COPD. An open-label, two-group, community-based, cluster-randomized controlled trial will be implemented in the semi-urban area of Pokhara Metropolitan city (former Lekhnath Municipality) located in the Kaski district of Nepal. The estimated sample size of the intervention will be 1143. The unit of randomization is the ward (administrative unit) of the study area. The follow-up survey will be conducted immediately after 12 months of FCHVs-led interventions. The difference in the rate of decline of forced expiratory volume in 1 s (FEV DISCUSSION: This study will estimate the burden of COPD, the magnitude of risk factors and generate evidence to mobilize community health workers for COPD prevention and management at the community level in Nepal.

trial registrationClinicalTrials.gov NCT03797768 . Registered on January 9, 2019.

Indexed as

Pulmonary Disease, Chronic ObstructiveQuality of LifeCommunity Health WorkersFemaleHumansNepalRandomized Controlled Trials as TopicVolunteersCluster randomized controlled trialCommunity health workersCOPDFemale Community Health VolunteersNepal

Identifiers

PMID34289879
PMCPMC8293490
OpenAlexW3184219221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.