Evidence map›Paper›PMID 34289866›Full record

ReviewJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2021

Dark-blood late gadolinium enhancement cardiovascular magnetic resonance for improved detection of subendocardial scar: a review of current techniques.

Robert J Holtackers, Caroline M Van De Heyning, Amedeo Chiribiri, Joachim E Wildberger, René M Botnar, M Eline Kooi

Abstract readReview
In one paragraph

Review in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert J HoltackersCardiovascular Research Institute Maastricht (CARIM), Maastricht University, PO Box 616, Maastricht, 6200 MD, The Netherlands. rob.holtackers@mumc.nl.ORCID 0000-0003-1809-313X
Caroline M Van De HeyningDepartment of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Amedeo ChiribiriSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.
Joachim E WildbergerCardiovascular Research Institute Maastricht (CARIM), Maastricht University, PO Box 616, Maastricht, 6200 MD, The Netherlands.
René M BotnarSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.
M Eline KooiCardiovascular Research Institute Maastricht (CARIM), Maastricht University, PO Box 616, Maastricht, 6200 MD, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For almost 20 years, late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) has been the reference standard for the non-invasive assessment of myocardial viability. Since the blood pool often appears equally bright as the enhanced scar regions, detection of subendocardial scar patterns can be challenging. Various novel LGE methods have been proposed that null or suppress the blood signal by employing additional magnetization preparation mechanisms. This review aims to provide a comprehensive overview of these dark-blood LGE methods, discussing the magnetization preparation schemes and findings in phantom, preclinical, and clinical studies. Finally, conclusions on the current evidence and limitations are drawn and new avenues for future research are discussed. Dark-blood LGE methods are a promising new tool for non-invasive assessment of myocardial viability. For a mainstream adoption of dark-blood LGE, however, clinical availability and ease of use are crucial.

Indexed as

GadoliniumMyocardial InfarctionCicatrixContrast MediaHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyPredictive Value of TestsReproducibility of ResultsContrast MediaGadoliniumCardiovascular diseasesLate gadolinium enhancementMagnetic resonance imagingMyocardial infarctionMyocardial scar

Identifiers

PMID34289866
PMCPMC8296731

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.