Evidence map›Paper›PMID 34289844›Full record

ArticleBMC veterinary research2021

The impact of vitamin E and/or selenium dietary supplementation on growth parameters and expression levels of the growth-related genes in broilers.

Olla A Khalifa, Rasha A Al Wakeel, Shabaan A Hemeda, Mohamed M Abdel-Daim, Ghadeer M Albadrani, Ahmad El Askary, Sabreen E Fadl, Fatma Elgendey

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  3. Strategies for Healthier Meat Foods: An Overview.Preventive nutrition and food science · 2024
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  5. The Interaction between Feed Bioactive Compounds and Chicken Genome.Animals : an open access journal from MDPI · 2023
    Review
  6. Article
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  8. Review
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Olla A KhalifaDepartment of Animal Wealth Development, Genetics and Genetic engineering, Faculty of veterinary medicine, Benha University, Benha, Egypt.
Rasha A Al WakeelDepartment of physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Shabaan A HemedaDepartment of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.
Mohamed M Abdel-DaimPharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt.
Ghadeer M AlbadraniDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Ahmad El AskaryDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O.Box 11099, Taif, 21944, Saudi Arabia.
Sabreen E FadlBiochemistry Dept., Faculty of Veterinary Medicine, Matrouh University, Matrouh, Egypt. nourmallak@yahoo.com.ORCID https://orcid.org/0000-0001-5541-6159
Fatma ElgendeyDepartment of Animal Wealth Development, Genetics and Genetic engineering, Faculty of veterinary medicine, Benha University, Benha, Egypt.
Benha University · EGAlexandria University · EGEgypt Nanotechnology Center · EGKafrelsheikh University · EGPrincess Nourah bint Abdulrahman University · SASuez Canal University · EGTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBroilers are continuously stressed because of the rapid growth rate and the environmental issues associated with industrialized poultry production systems, which lead to higher susceptibility for infection with pathogens. It is well known that vitamin E (Vit. E) and selenium (Se) supplementation have protective functions in such stressful conditions. This protocol was to investigate the impact of Vit. E and/or Se on the production performance, some serum biochemistry, and expression of some growth-related gene in the liver tissue of the broilers. The day-old chicks were allotted into four groups according to the supplement; Control group and groups supplemented with Vit. E and/or Se into Vit. E group (100 mg Vit. E/kg diet), Se group (0.3 mg sodium selenite/kg diet), and Vit E + Se group that supplemented with both Vit. E and Se.

resultsThe data of the present experiment showed that dietary inclusion of Vit. E and/or Se significantly (P ≤ 0.05) improved the production parameters without any side effect on the general health status of the broilers, which indicated by normal serum biochemical parameters. Moreover, the treatments positively affected the expression of some genes related to growth performance including growth hormone receptor (GHR) and insulin-like growth factor 1 (IGF1) in the liver tissue of broilers.

conclusionDietary supplementation of Vit. E and/or Se improved the production parameters and upregulate the growth-related genes without effect on the general health status of the broilers.

Indexed as

Animal FeedAnimal Nutritional Physiological PhenomenaAnimalsChickensDietDietary SupplementsGene Expression RegulationSeleniumVitamin ESeleniumVitamin EBiochemistryBroilersGene expressionGrowth performanceSeleniumVitamin E

Identifiers

PMID34289844
PMCPMC8293533
OpenAlexW3186044439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.