Evidence map›Paper›PMID 34289825›Full record

ArticleBMC public health2021

Environmental assessment of pediatric Lead exposure in Tehran; a prospective cross-sectional study.

Hedieh Ahangar, Afsoon Karimdoost, Amir Salimi, Maryam Akhgari, Scott Phillips, Nasim Zamani, Nasibeh Hassanpour, Ali-Asghar Kolahi, Gary R Krieger, Hossein Hassanian-Moghaddam

Abstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hedieh AhangarPharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran.
Afsoon KarimdoostPharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran.
Amir SalimiSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Maryam AkhgariLegal Medicine Research Center, Iranian Legal Medicine Organization, Tehran, Iran.
Scott PhillipsUniversity of Colorado Anchutz Medical Campus, Rocky Mountain Poison & Drug Safety, Denver, CO and Washington Poison Center, Seattle, WA, USA.
Nasim ZamaniSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nasibeh HassanpourPharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran.
Ali-Asghar KolahiSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Gary R KriegerSkaggs School of Pharmacy and Pharmaceutical Science, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
Hossein Hassanian-MoghaddamSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. hassanian@sbmu.ac.ir.ORCID 0000-0003-4370-0544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIngestion and inhalation are common routes of exposure for lead in humans. Developing countries still have unacceptably high rates of lead toxicity, especially in children. Studies on probable risk factors of lead poisoning in Iranian children are insufficient. In this study, we aimed to evaluate possible environmental factors in children with high blood lead concentrations living in Tehran and neighboring cities.

methodsIn a prospective cross-sectional study between March 2018 and March 2019 we followed all children referred from two pediatric gastrointestinal clinics with blood lead level (BLL) > 5 μg/dL in metropolitan Tehran to investigate possible environmental risk factors in their home. Household specimens including scratched wall paint, house floor dust, windowsill dust, tap water, and consumed spice were evaluated using atomic absorption method to detect lead concentrations. Epidemiological and environmental data collected through in-depth interviews with parents/guardians. Industrial areas were defined based on municipality maps on industrial places.

resultsThirty of 56 parents/guardians with BLL > 5 μg/dL agreed to be followed through environmental investigation. The only categorical statistically significant risk factor was a history of lead poisoning in the family and living in an industrial zone. There was a positive correlation between BLL and interior windowsills dust lead level, r = 0.46, p = 0.01. Scratched paint lead level and BLL showed a significant positive correlation, r = 0.50, p = 0.005. House floor dust lead level (median = 77.4, p < 0.001) and interior windowsill dust lead level (median = 291, p = 0.011) were both significantly higher than the environmental protection agency (EPA) standards of 40 μg/ft

conclusionChildren's playing environment should be cleaned more often to reduce dust. Moreover, specific rules may need to be implemented for paint lead concentrations and air pollution, especially in industrial areas.

Indexed as

LeadLead PoisoningChildCitiesCross-Sectional StudiesDustEnvironmental ExposureHumansIranProspective StudiesDustLeadChildrenLead toxicityPlumbismTrace elements

Identifiers

PMID34289825
PMCPMC8296531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.