ArticleThe Korean journal of internal medicine2021
The Korean Hypertension Cohort study: design and baseline characteristics.
Article in The Korean journal of internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Time to death and its predictors among adult hypertensive patients attending public health facilities, Dire Dawa, Eastern Ethiopia: Retrospective cohort study.Journal of public health research · 2025Article
- Information and Communications Technology-Based Monitoring Service for Tailored Chronic Disease Management in Primary Care: Cost-Effectiveness Analysis Based on ICT-CM Trial Results.Journal of medical Internet research · 2024Article
- Association between office visit intervals and long-term cardiovascular risk in hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Clinical and epidemiological implications of the data on the Korean clinical hypertension cohort.The Korean journal of internal medicine · 2023Article
- Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort.The Korean journal of internal medicine · 2023Article
- The Promising First Cohort Study in Korean Patients with Obesity and Overweight: Gangwon Obesity and Metabolic Syndrome Study.Journal of obesity & metabolic syndrome · 2022Article
- Comparison of the efficiency between electrocardiogram and echocardiogram for left ventricular hypertrophy evaluation in patients with hypertension: Insight from the Korean Hypertension Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Heart Failure and Diabetes Mellitus: Dangerous Liaisons.International journal of heart failure · 2022Review
- Development of a Korean-specific cardiovascular risk model in a cohort at high-risk of hypertension.The Korean journal of internal medicine · 2021Article
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Abstract
BACKGROUND/
aimsHypertension (HT) has a significant impact on public health and medical expenses. However, HT is a chronic disease that requires the long-term follow-up of a large number of patients.
methodsThe Korean Hypertension Cohort (KHC) study aimed to develop a model for calculating cardiovascular risk in HT patients by linking and utilizing the detailed clinical and longitudinal data from hospitals and the national health insurance claim database, respectively. This cohort had a planned sample size of over 11,000 HT patients and 100,000 non-HT controls. Eligible patients were hypertensive patients, who were presenting for the first time and were diagnosed with HT as a main disease from 2006 to 2011. Long-term survival data over a period of approximately 9 years were obtained from the national health insurance claim and national health examination data.
resultsThis cohort enrolled 11,083 patients with HT. The mean age was 58.87 ± 11.5 years, 50.5% were male, and 31.4% were never-treated HT. Of the enrolled patients, 32.9% and 37.7% belonged to the high and moderate cardiovascular risk groups, respectively. Initial blood pressures were 149.4 ± 18.5/88.5 ± 12.5 mmHg. During the 2 years hospital data follow-up period, blood pressures lowered to 130.8 ± 14.1/78.0 ± 9.7 mmHg with 1.9 ± 1.0 tablet doses of antihypertensive medication. Cardiovascular events occurred in 7.5% of the overall patients; 8.5%, 8.8%, and 4.7% in the high, moderate, and low risk patients, respectively.
conclusionThe KHC study has provided important information on the long-term outcomes of HT patients according to the blood pressure, comorbid diseases, medication, and adherence, as well as health behaviors and health resource use.
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