ArticleAging2021
Association between carotid artery perivascular fat density and cerebral small vessel disease.
Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Targeting perivascular adipose tissue in vascular aging: innovative translational strategies for disease prevention and monitoring.Apoptosis : an international journal on programmed cell death · 2026Review
- Pericarotid fat density: a novel predictor of cognitive and functional outcomes in cerebral small vessel disease.Frontiers in aging neuroscience · 2026Article
- Carotid napkin-ring sign plaques are associated with early neurological deterioration in lenticulostriate artery branch atheromatous disease.Frontiers in neurology · 2026Article
- Interpretable machine learning for detecting symptomatic patients with carotid atherosclerosis on computed tomography angiography: a retrospective diagnostic study.BMC medical imaging · 2025Article
- A new predictor of disease activity in Takayasu's arteritis patients: pericarotid fat density.BMC medical imaging · 2025Article
- Association between pericarotid fat attenuation index and clinical outcomes of symptomatic cerebral small vessel disease.Quantitative imaging in medicine and surgery · 2025Article
- Carotid Pericarotid Fat Density: A New Predictor of Recurrent Ischemic Stroke or Transient Ischemic Attack.Journal of atherosclerosis and thrombosis · 2025Article
- Predicting progression of cerebral small vessel disease: relevance of carotid perivascular fat density based on computed tomography angiography.Quantitative imaging in medicine and surgery · 2025Article
- Shear Wave Elastography for Carotid Artery Stiffness: Ready for Prime Time?Diagnostics (Basel, Switzerland) · 2025Review
- Evaluation of risk factors for acute stroke using combined CTA and MR HR-VWI imaging.Frontiers in neurology · 2025Review
- Pericarotid Fat as a Marker of Cerebrovascular Risk.AJNR. American journal of neuroradiology · 2024Review
- A new predictor of coronary artery disease in acute ischemic stroke or transient ischemic attack patients: pericarotid fat density.European radiology · 2024Article
- Peri-Carotid Adipose Tissue and Atherosclerosis at Carotid Bifurcation.Journal of cardiovascular development and disease · 2024Article
- Article
- Napkin-ring sign plaques are associated with clinical outcome in patients with acute ischemic stroke after endovascular therapy.Frontiers in neurologyArticle
- CT angiography-derived plaque and perivascular fat radiomics for predicting ipsilateral stroke recurrence in patients with carotid atherosclerosis.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies aiming to identify the significance of the carotid artery perivascular fat density are limited. The present study investigated the distribution pattern of pericarotid fat and its association with imaging markers of cerebral small vessel disease (CSVD). In total, 572 subjects who underwent both neck computed tomography angiography and cranial magnetic resonance imaging were analyzed. The pericarotid fat density near the origin of the internal carotid artery (ICA) and imaging markers of CSVD, such as lacunes, white matter hyperintensities (WMHs) and dilated perivascular spaces (PVSs), were assessed. We found that an increased pericarotid fat density was associated with the presence of lacunes and a higher WMH grade in all subjects, but in the patients with acute ischemic stroke, there was a difference only among the WMH grades. There was no significant difference in the pericarotid fat density in different grades of PVSs. The patients with acute ischemic stroke had a significantly higher mean pericarotid fat density than those without stroke. In conclusion, our study provides evidence suggesting that an increased pericarotid fat density is associated with the presence and degree of WMHs and lacunes. Our findings suggested that features that appear to extend beyond the vessel lumen of the ICA may be linked to CSVD.
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