Evidence map›Paper›PMID 34289387›Full record

ArticleCurrent biology : CB2021

Spinal V1 neurons inhibit motor targets locally and sensory targets distally.

Mohini Sengupta, Vamsi Daliparthi, Yann Roussel, Tuan V Bui, Martha W Bagnall

Abstract read
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Inhibitory circuits control leg movements duringbioRxiv : the preprint server for biology · 2025
    Article
  6. V2b Neurons Act via Multiple Targets to Produce in Phase Inhibition during Locomotion.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Spinal Basis of Direction Control during Locomotion in Larval Zebrafish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Mohini SenguptaWashington University School of Medicine, Department of Neuroscience, St. Louis, MO, USA.
Vamsi DaliparthiWashington University School of Medicine, Department of Neuroscience, St. Louis, MO, USA.
Yann RousselBrain and Mind Research Institute, Centre for Neural Dynamics, Department of Biology, University of Ottawa, Ottawa, Canada; Blue Brain Project, École Polytechnique Fédérale de Lausanne, Geneve, Switzerland.
Tuan V BuiBrain and Mind Research Institute, Centre for Neural Dynamics, Department of Biology, University of Ottawa, Ottawa, Canada.
Martha W BagnallWashington University School of Medicine, Department of Neuroscience, St. Louis, MO, USA. Electronic address: bagnall@wustl.edu.

Funding

SYNAPTIC COMPUTATIONS IN CENTRAL VESTIBULAR NEURONSR01DC016413 · NIDCD · WASHINGTON UNIVERSITY · PI Martha W Bagnall · 2018 to 2026
$2.8M
NIDCD NIH HHS R01 DC016413
6 · The paper itself

Abstract

Rostro-caudal coordination of spinal motor output is essential for locomotion. Most spinal interneurons project axons longitudinally to govern locomotor output, yet their connectivity along this axis remains unclear. In this study, we use larval zebrafish to map synaptic outputs of a major inhibitory population, V1 (Eng1

Indexed as

Motor NeuronsZebrafishAnimalsInterneuronsLocomotionSpinal Corddifferential connectivitymotorrostro-caudal coordinationspinal cordzebrafish

Identifiers

PMID34289387
PMCPMC8440420

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.