Evidence map›Paper›PMID 34289277›Full record

ArticleThe New England journal of medicine2021

Racial Inequality in Prescription Opioid Receipt - Role of Individual Health Systems.

Nancy E Morden, Deanna Chyn, Andrew Wood, Ellen Meara

Open access · bronzeAbstract read
In one paragraph

Article in The New England journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 2 pooled it
25.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 2 syntheses or guidelines pooled it, 167 citations in OpenAlex.

  1. Opioid conversion in adults with cancer: MASCC-ASCO-AAHPM-HPNA-NICSO guideline.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Guideline
  2. CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2022
    Guideline
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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nancy E MordenFrom the Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH (N.E.M., D.C., A.W., E.M.); UnitedHealthcare, Minnetonka, MN (N.E.M.); and the Harvard T.H. Chan School of Public Health, Boston (E.M.), and the National Bureau of Economic Research, Cambridge (E.M.) - both in Massachusetts.
Deanna ChynFrom the Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH (N.E.M., D.C., A.W., E.M.); UnitedHealthcare, Minnetonka, MN (N.E.M.); and the Harvard T.H. Chan School of Public Health, Boston (E.M.), and the National Bureau of Economic Research, Cambridge (E.M.) - both in Massachusetts.
Andrew WoodFrom the Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH (N.E.M., D.C., A.W., E.M.); UnitedHealthcare, Minnetonka, MN (N.E.M.); and the Harvard T.H. Chan School of Public Health, Boston (E.M.), and the National Bureau of Economic Research, Cambridge (E.M.) - both in Massachusetts.
Ellen MearaFrom the Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH (N.E.M., D.C., A.W., E.M.); UnitedHealthcare, Minnetonka, MN (N.E.M.); and the Harvard T.H. Chan School of Public Health, Boston (E.M.), and the National Bureau of Economic Research, Cambridge (E.M.) - both in Massachusetts.
National Bureau of Economic Research · US

Funding

UNDERSTANDING AND IMPROVING EPISODE-BASED HOSPITAL CAREP01AG019783 · NIA · DARTMOUTH COLLEGE · PI Alistair James O'MALLEY · 2001 to 2026
$52.9M
PA-20-072: Accelerating the Use of Evidence-based Innovation in Healthcare SystemsU19HS024075 · AHRQ · DARTMOUTH COLLEGE · PI MEARA, ELLEN R. · 2015 to 2021
$19.8M
Agency for Healthcare Research and Quality 1U19HS024075AHRQ HHS U19 HS024075NIA NIH HHS AG019783NIA NIH HHS P01 AG019783
6 · The paper itself

Abstract

backgroundHistorically, the receipt of prescription opioids has differed among racial groups in the United States. Research has not sufficiently explored the contribution of individual health systems to these differences by examining within-system prescription opioid receipt according to race.

methodsWe used 2016 and 2017 Medicare claims data from a random 40% national sample of fee-for-service, Black and White beneficiaries 18 to 64 years of age who were attributed to health systems. We identified 310 racially diverse systems (defined as systems with ≥200 person-years each for Black and White patients). To test representativeness, we compared patient characteristics and opioid receipt among the patients in these 310 systems with those in the national sample. Within the 310 systems, regression models were used to explore the difference between Black and White patients in the following annual opioid measures: any prescription filled, short-term receipt of opioids, long-term receipt of opioids (one or more filled opioid prescriptions in all four calendar quarters of a year), and the opioid dose in morphine milligram equivalents (MME); models controlled for patient characteristics, state, and system.

resultsThe national sample included 2,197,153 person-years, and the sample served by 310 racially diverse systems included 896,807 person-years (representing 47.4% of all patients and 56.1% of Black patients in the national sample). The national sample and 310-systems sample differed meaningfully only in the percent of person-years contributed by Black patients (21.3% vs. 25.9%). In the 310-systems sample, the crude annual prevalence of any opioid receipt differed slightly between Black and White patients (50.2% vs. 52.2%), whereas the mean annual dose was 36% lower among Black patients than among White patients (5190 MME vs. 8082 MME). Within systems, the adjusted race differences in measures paralleled the population trends: the annual prevalence of opioid receipt differed little, but the mean annual dose was higher among White patients than among Black patients in 91% of the systems, and at least 15% higher in 75% of the systems.

conclusionsWithin individual health systems, Black and White patients received markedly different opioid doses. These system-specific findings could facilitate exploration of the causes and consequences of these differences. (Funded by the National Institute on Aging and the Agency for Healthcare Research and Quality.).

Indexed as

AdolescentAdultAnalgesics, OpioidBlack or African AmericanFemaleHealthcare DisparitiesHealth ServicesHumansMaleMedicareMiddle AgedPain ManagementPersons with DisabilitiesPractice Patterns, Physicians'Prescription DrugsUnited StatesAnalgesics, OpioidPrescription Drugs

Identifiers

PMID34289277
PMCPMC8402927
OpenAlexW3184061490

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.