Evidence map›Paper›PMID 34289271›Full record

ArticleThe New England journal of medicine2021

ChAdOx1 nCoV-19 Vaccine Efficacy against the B.1.351 Variant. Reply.

Shabir A Madhi, Alane Izu, Andrew J Pollard

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in The New England journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05077176 (Open Label, Multi-Center Phase 3 Clinical Trial to Determine Safety, Efficacy, and Immunogenicity of Booster Vaccination Against SARS-CoV-2), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05077176 phase3completednot on this map

Open Label, Multi-Center Phase 3 Clinical Trial to Determine Safety, Efficacy, and Immunogenicity of Booster Vaccination Against SARS-CoV-2

TypeinterventionalSponsorHealth Institutes of TurkeyRan2021 to 2024Enrolled4,340ConditionsCOVID-19, Sars-CoV-2 InfectionArmsCoronaVac, Turkovac
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Post-Vaccination Coronavirus Disease 2019: A Case-Control Study and Genomic Analysis of 119 Breakthrough Infections in Partially Vaccinated Individuals.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  5. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Africa: Current Considerations and Future Projections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. SARS-CoV-2 spike therapeutic antibodies in the age of variants.The Journal of experimental medicine · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Shabir A MadhiUniversity of the Witwatersrand, Johannesburg, South Africa.
Alane IzuUniversity of the Witwatersrand, Johannesburg, South Africa.
Andrew J PollardUniversity of Oxford, Oxford, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19VaccinesChAdOx1 nCoV-19COVID-19 VaccinesHumansSARS-CoV-2ChAdOx1 nCoV-19COVID-19 VaccinesVaccines

Identifiers

PMID34289271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.