Evidence map›Paper›PMID 34288963›Full record

ArticlePloS one2021

Survival prognostic factors in patients with acute myeloid leukemia using machine learning techniques.

Keyvan Karami, Mahboubeh Akbari, Mohammad-Taher Moradi, Bijan Soleymani, Hossein Fallahi

Abstract readValidation Study
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keyvan KaramiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0002-1875-6741
Mahboubeh AkbariDepartment of Statistics, Ferdowsi University of Mashhad, Mashhad, Iran.
Mohammad-Taher MoradiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Bijan SoleymaniMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Hossein FallahiDepartment of Biology, School of Sciences, Razi University, Kermanshah, Iran.ORCID 0000-0002-8754-3491

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper identifies prognosis factors for survival in patients with acute myeloid leukemia (AML) using machine learning techniques. We have integrated machine learning with feature selection methods and have compared their performances to identify the most suitable factors in assessing the survival of AML patients. Here, six data mining algorithms including Decision Tree, Random Forrest, Logistic Regression, Naive Bayes, W-Bayes Net, and Gradient Boosted Tree (GBT) are employed for the detection model and implemented using the common data mining tool RapidMiner and open-source R package. To improve the predictive ability of our model, a set of features were selected by employing multiple feature selection methods. The accuracy of classification was obtained using 10-fold cross-validation for the various combinations of the feature selection methods and machine learning algorithms. The performance of the models was assessed by various measurement indexes including accuracy, kappa, sensitivity, specificity, positive predictive value, negative predictive value, and area under the ROC curve (AUC). Our results showed that GBT with an accuracy of 85.17%, AUC of 0.930, and the feature selection via the Relief algorithm has the best performance in predicting the survival rate of AML patients.

Indexed as

Machine LearningModels, BiologicalAdolescentAdultAgedAged, 80 and overDisease-Free SurvivalFemaleHumansLeukemia, Myeloid, AcuteMaleMiddle AgedPredictive Value of TestsRisk FactorsSurvival Rate

Identifiers

PMID34288963
PMCPMC8294525

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.