Evidence map›Paper›PMID 34288958›Full record

ArticlePloS one2021

A power approximation for the Kenward and Roger Wald test in the linear mixed model.

Sarah M Kreidler, Brandy M Ringham, Keith E Muller, Deborah H Glueck

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In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah M KreidlerDepartment of Biostatistics and Informatics, University of Colorado Denver, Aurora, CO, United States of America.
Brandy M RinghamLEAD Center, University of Colorado Denver, Aurora, CO, United States of America.ORCID 0000-0001-5677-373X
Keith E MullerDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, United States of America.
Deborah H GlueckDepartment of Pediatrics, University of Colorado Denver, Aurora, CO, United States of America.

Funding

The Early Life Exposome and Childhood Health - The Colorado Healthy Start 3 Cohort StudyUG3OD023248 · OD · UNIVERSITY OF COLORADO DENVER · PI BEKELMAN, TRACI ALLISON, DABELEA, DANA · 2016 to 2024
$5.9M
Methods and Software for Lifecourse Epidemiology Data and Sample Size AnalysisR01GM121081 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI DABELEA, DANA, GLUECK, DEBORAH HELEN · 2016 to 2019
$2.6M
Multilevel and Longitudinal Study Sample Size Tools for Behavioral ScientistsR01DE020832 · NIDCR · UNIVERSITY OF FLORIDA · PI MULLER, KEITH E · 2011 to 2014
$2.3M
NIDCR NIH HHS R01 DE020832NIGMS NIH HHS R01 GM121081NIH HHS UG3 OD023248
6 · The paper itself

Abstract

We derive a noncentral [Formula: see text] power approximation for the Kenward and Roger test. We use a method of moments approach to form an approximate distribution for the Kenward and Roger scaled Wald statistic, under the alternative. The result depends on the approximate moments of the unscaled Wald statistic. Via Monte Carlo simulation, we demonstrate that the new power approximation is accurate for cluster randomized trials and longitudinal study designs. The method retains accuracy for small sample sizes, even in the presence of missing data. We illustrate the method with a power calculation for an unbalanced group-randomized trial in oral cancer prevention.

Indexed as

Computer SimulationModels, BiologicalHumansLinear ModelsMonte Carlo MethodNeoplasmsRandomized Controlled Trials as TopicSample Size

Identifiers

PMID34288958
PMCPMC8294572

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.