Evidence map›Paper›PMID 34288808›Full record

ArticleBioengineered2021

Laboratory characteristics analysis of the efficacy of levothyroxine on subclinical hypothyroidism during pregnancy: a single-center retrospective study.

Luyang Han, Yan Ma, Zhaoxia Liang, Danqing Chen

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Homocysteine and thyroid diseases.Frontiers in endocrinology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Luyang HanDepartment of Obstetrics, Women's Hospital School of Medicine Zhejiang University, Hangzhou, China.
Yan MaDepartment of Obstetrics, Women's Hospital School of Medicine Zhejiang University, Hangzhou, China.
Zhaoxia LiangDepartment of Obstetrics, Women's Hospital School of Medicine Zhejiang University, Hangzhou, China.
Danqing ChenDepartment of Obstetrics, Women's Hospital School of Medicine Zhejiang University, Hangzhou, China.
Women's Hospital, School of Medicine, Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To reassess the efficacy of levothyroxine on subclinical hypothyroidism (SCH, 4.0 mIU/L ≤ TSH (thyroid stimulating hormone) <10 mIU/L with normal free T4) during pregnancy. 165 levothyroxine-treated pregnant women experiencing SCH were screened. And controls were randomly selected using euthyroidism (EU) women, matched by age, gravidity, and parity in the EU group (

Indexed as

HypothyroidismPregnancy ComplicationsAdultFemaleHomocysteineHumansLipoproteinsPregnancyPregnancy OutcomeRetrospective StudiesThyroxineTreatment OutcomeHomocysteineLipoproteinsThyroxinehomocysteineHypothyroidismlevothyroxinelipoproteinspregnancy outcome

Identifiers

PMID34288808
PMCPMC8806776
OpenAlexW3184185048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.