Evidence map›Paper›PMID 34288703›Full record

ArticleApplied and environmental microbiology2021

Functional Expression of Two Unusual Acidic Peroxygenases from

Patricia Gomez de Santos, Manh Dat Hoang, Jan Kiebist, Harald Kellner, René Ullrich, Katrin Scheibner, Martin Hofrichter, Christiane Liers, Miguel Alcalde

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Empowering Precision C-H Functionalization: Advances in Peroxygenase Engineering.Angewandte Chemie (International ed. in English) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Rapid screening system to identify unspecific peroxygenase activity.Clinical hemorheology and microcirculation · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Patricia Gomez de SantosDepartment of Biocatalysis, Institute of Catalysis, CSIC, Madrid, Spain.
Manh Dat HoangDepartment of Biocatalysis, Institute of Catalysis, CSIC, Madrid, Spain.
Jan KiebistJenaBios GmbH, Jena, Germany.
Harald KellnerDepartment of Bio- and Environmental Sciences, TU Dresden, International Institute Zittau, Zittau, Germany.
René UllrichDepartment of Bio- and Environmental Sciences, TU Dresden, International Institute Zittau, Zittau, Germany.
Katrin ScheibnerInstitute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.
Martin HofrichterDepartment of Bio- and Environmental Sciences, TU Dresden, International Institute Zittau, Zittau, Germany.
Christiane LiersDepartment of Bio- and Environmental Sciences, TU Dresden, International Institute Zittau, Zittau, Germany.
Miguel AlcaldeDepartment of Biocatalysis, Institute of Catalysis, CSIC, Madrid, Spain.ORCID 0000-0001-6780-7616
International University Institute · DEInstituto de Catálisis y Petroleoquímica · ESBrandenburg University of Technology Cottbus-Senftenberg · DEJena Bioscience (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal unspecific peroxygenases (UPOs) are emergent biocatalysts that perform highly selective C-H oxyfunctionalizations of organic compounds, yet their heterologous production at high levels is required for their practical use in synthetic chemistry. Here, we achieved functional expression of two new unusual acidic peroxygenases from

Indexed as

AgaricalesBioreactorsFermentationMixed Function OxygenasesMutationPichiaProtein EngineeringSaccharomyces cerevisiaeMixed Function Oxygenasesperoxygenasedirected evolutionheterologous functional expressionPichia pastorisSaccharomyces cerevisiaeunspecific peroxygenase

Identifiers

PMID34288703
PMCPMC8432526
OpenAlexW3185753147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.