Evidence map›Paper›PMID 34288349›Full record

ArticleEMBO reports2021

Exophers to feed them all.

Erin J Cram

Open access · bronzeAbstract readComment
In one paragraph

Article in EMBO reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  6. Review
  7. Exophers to feed them all.EMBO reports · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Erin J CramDepartment of Biology, Northeastern University, Boston, MA, USA.ORCID 0000-0002-8129-1326
Northeastern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells release extracellular vesicles to remove damaged components and communicate with other cells via packets of proteins, lipids, and RNAs. Neuronal cells in the nematode C. elegans release particularly large extracellular vesicles, known as exophers, to rid themselves of damaged organelles and protein aggregates. Turek et al now demonstrate a new role for these vesicles: Embryos in the uterus stimulate body wall muscle cells to release exophers laden with yolk, which are taken up by oocytes to nourish the next set of embryos (Turek et al, 2021).

Indexed as

Caenorhabditis elegansExtracellular VesiclesAnimalsFemaleNeuronsOocytesOrganelles

Identifiers

PMID34288349
PMCPMC8339668
OpenAlexW3186241488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.