ArticleThe oncologist2021
Impact of Sociodemographic Disparities and Insurance Status on Survival of Patients with Early-Onset Colorectal Cancer.
Article in The oncologist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 46 citations in OpenAlex.
- Distance to Care, Regional Context, and Survival in Early-Onset Colorectal Cancer.Journal of surgical oncology · 2026Article
- Identifying clinical and lifestyle factor mediators of the association between socioeconomic status and colorectal cancer mortality.SSM - population health · 2026Article
- Medicaid Expansion and Mortality Among Patients With Colorectal Cancer.JAMA network open · 2026Article
- Socioeconomic disparities in survival of patients with superficial colorectal cancer.Discover oncology · 2026Article
- Divided care, diminished outcomes? The impact of care fragmentation on survival in glioblastoma.Journal of neuro-oncology · 2026Article
- Impact of socioeconomic status on patient characteristics and postoperative outcomes in colorectal cancer surgery: A retrospective cohort study.International journal of colorectal disease · 2026Article
- Survival differences after diagnosis of early-onset colorectal cancer by race and ethnicity and neighborhood-level socioeconomic status.Journal of colon and rectal cancer · 2026Article
- Local and National Trends in Emergency Presentation of Colon and Rectal Cancer.Journal of surgical oncology · 2025Article
- Socioeconomic status impacts tumor biology, treatment, and outcomes in over 200,000 patients with invasive lobular carcinoma of the breast: an analysis of the National Cancer Database.Breast cancer research and treatment · 2025Article
- Comprehensive Analysis of Native Hawaiians and Other Pacific Islanders with Early Onset Colorectal Cancer.Journal of gastrointestinal cancer · 2025Article
- Early-onset gastrointestinal cancers: comprehensive review and future directions.The British journal of surgery · 2025Review
- Beyond Barriers: Achieving True Equity in Cancer Care.Current oncology (Toronto, Ont.) · 2025Review
- Outcomes for Medicaid Patients with Colorectal Cancer Are Improved in Affluent Neighborhoods, but Disparities Persist.Cancers · 2025Article
- Differential Colorectal Cancer Mortality Across Racial and Ethnic Groups: Impact of Socioeconomic Status, Clinicopathology, and Treatment-Related Factors.Cancer medicine · 2025Article
- Medicaid Expansion and Overall Survival of Lower Gastrointestinal Cancer Patients After Cytoreductive Surgery and Heated Intraperitoneal Chemotherapy.Annals of surgical oncology · 2025Article
- Closing the Gap: Approaches to Improving Colorectal Surgery Care for the Uninsured and Underinsured.Clinics in colon and rectal surgery · 2025Review
- Early-Onset Colorectal Cancer Survival by Race and Ethnicity in a Large Community-Based Insured Population.Gastro hep advances · 2025Article
- Multi-faceted strategies to advance health equity in colorectal cancer screening in primary care setting: quality improvement project.BMC health services research · 2024Article
- Racial and Ethnic Variation in Survival in Early-Onset Colorectal Cancer.JAMA network open · 2024Article
- Disparities in Colorectal Cancer Presentation at a National Cancer Institute-Designated Cancer Center and a Safety-Net Hospital during the COVID-19 Pandemic.Medical research archives · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow socioeconomic status (SES) has been linked to worse survival in patients with colorectal cancer (CRC); however, the impact of SES on early-onset CRC remains undescribed. MATERIALS AND
methodsRetrospective analysis of data from the National Cancer Database (NCDB) between 2004 and 2016 was conducted. We combined income and education to form a composite measure of SES. Logistic regression and χ
resultsIn total, 30,903 patients with early-onset CRC were identified, of whom 78.7% were White; 14.5% were Black. Low SES compared with high SES patients were more likely to be Black (26.3% vs. 6.1%) or Hispanic (25.3% vs. 10.5%), have T4 tumors (21.3% vs. 17.8%) and/or N2 disease (13% vs. 11.1%), and present with stage IV disease (32.8% vs. 27.7%) at diagnosis (p < .0001, all comparisons). OS gradually improved with increasing SES at all disease stages (p < .001). In stage IV, the 5-year survival rate was 13.9% vs. 21.7% for patients with low compared with high SES. In multivariable analysis, SES (low vs. high group; adjusted hazard ratio [HR
conclusionPatients with early-onset CRC with low SES had the worst outcomes. Our data suggest that SES should be considered when implementing programs to improve the early detection and treatment of patients with early-onset CRC. IMPLICATIONS FOR PRACTICE: Low socioeconomic status (SES) has been linked to worse survival in patients with colorectal cancer (CRC); however, the impact of SES on early-onset CRC remains undescribed. In this retrospective study of 30,903 patients with early-onset CRC in the National Cancer Database, a steady increase in the yearly rate of stage IV diagnosis at presentation was observed. The risk of death increased as socioeconomic status decreased. Race and insurance status were independent predictors for survival. Implementation of programs to improve access to care and early diagnostic strategies among younger adults, especially those with low SES, is warranted.
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