Evidence map›Paper›PMID 34288218›Full record

ReviewPsycho-oncology2021

Evidence of psychological and biological effects of structured Mindfulness-Based Interventions for cancer patients and survivors: A meta-review.

Juliana Pedro, Sara Monteiro-Reis, Carina Carvalho-Maia, Rui Henrique, Carmen Jerónimo, Eunice R Silva

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Psycho-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05847153 (The Mindful and Self-Compassionate Care Program Aim 2), which is not on this map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
2.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05847153 nacompletednot on this mapstarted 2023, after this paper: background citation

The Mindful and Self-Compassionate Care Program Aim 2

TypeinterventionalSponsorMassachusetts General HospitalRan2023 to 2024Enrolled13ConditionsAlzheimer Disease and Related Dementias, Dementia AlzheimersArmsMASC
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Mindfulness-based interventions for addressing sexual function after cancer: A systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Effects of a 4Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Trial
  7. Trial
  8. Article
  9. Article
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  11. Global landscape and hotspot analysis of meditation research in cancer: a bibliometric study.Journal of cancer survivorship : research and practice · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Effects of a Single Session of Mindfulness and Compassion on Skin Temperature in Breast Cancer Survivors.International journal of environmental research and public health · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Juliana PedroPsychology Service, Portuguese Oncology Institute of Porto (IPOP), Porto, Portugal.ORCID 0000-0003-1959-4921
Sara Monteiro-ReisCancer Biology & Epigenetics Group, Research Center, Portuguese Oncology Institute of Porto (CI-IPOP), Porto, Portugal.ORCID 0000-0002-2193-2793
Carina Carvalho-MaiaCancer Biology & Epigenetics Group, Research Center, Portuguese Oncology Institute of Porto (CI-IPOP), Porto, Portugal.ORCID 0000-0002-7011-8341
Rui HenriqueCancer Biology & Epigenetics Group, Research Center, Portuguese Oncology Institute of Porto (CI-IPOP), Porto, Portugal.ORCID 0000-0003-3171-4666
Carmen JerónimoCancer Biology & Epigenetics Group, Research Center, Portuguese Oncology Institute of Porto (CI-IPOP), Porto, Portugal.ORCID 0000-0003-4186-5345
Eunice R SilvaPsychology Service, Portuguese Oncology Institute of Porto (IPOP), Porto, Portugal.ORCID 0000-0002-3403-6058
Instituto Português de Oncologia Francisco Gentil · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA large number of studies have been conducted exploring the effects of mindfulness programs on health outcomes, such as psychological and biological outcomes. However, there is substantial heterogeneity among studies and, consequently, in the systematic reviews/meta-analyses. Since clinical practice is massively informed by evidence on review studies, our main objective was to summarize the reported evidence regarding the effects of structured mindfulness-based programs on psychological, biological, and quality-of-life outcomes in cancer patients.

methodsWe conducted a meta-review, using a literature search from inception to June 2020 in several electronic databases using a combination of keywords including MBSR, MBCT, cancer, and meta-analysis OR "systematic review" (PROSPERO registration CRD42020186511).

resultsTen studies met the eligibility criteria and were included. The main findings were beneficial small to medium effect sizes of Mindfulness-Based Stress Reduction (MBSR)/Mindfulness-Based Cognitive Therapy (MBCT)/Mindfulness-Based Cancer Recovery (MBCR) on psychological health, such as anxiety, depression, stress, and quality of life. A beneficial effect was found for biological outcomes, albeit based on a reduced number of studies. Studies were moderate homogenous regarding the intervention, population, and outcomes explored. Results on long-term follow-up seem to indicate that the effects tend not to be maintained, namely in shorter follow-ups (6 months).

conclusionsThis meta-review brings a broad perspective on the actual evidence regarding MBSR/MBCT/MBCR. We expect to contribute to future project design, focused on developing high-quality studies and exploring the moderating effects that might contribute to biased results, as well as exploring who might benefit more from MBSR/MBCT/MBCT interventions.

Indexed as

MindfulnessNeoplasmsHumansQuality of LifeStress, PsychologicalSurvivorsanxietycancerimmune responseinflammatory-related markersMBCTMBSRmeta-reviewmindfulnessoncologypsychological

Identifiers

PMID34288218
PMCPMC9290489
OpenAlexW3183683794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.