Evidence map›Paper›PMID 34288025›Full record

ArticleAmerican journal of industrial medicine2021

Cancer survival among World Trade Center rescue and recovery workers: A collaborative cohort study.

David G Goldfarb, Rachel Zeig-Owens, Dana Kristjansson, Jiehui Li, Robert M Brackbill, Mark R Farfel, James E Cone, Amy R Kahn, Baozhen Qiao, Maria J Schymura and 7 more

Abstract read
In one paragraph

Article in American journal of industrial medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

David G GoldfarbDepartment of Medicine, Montefiore Medical Center, New York, New York, USA.ORCID 0000-0003-2682-7543
Rachel Zeig-OwensDepartment of Medicine, Montefiore Medical Center, New York, New York, USA.ORCID 0000-0002-8679-2306
Dana KristjanssonDepartment of Hematology and Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, New York, USA.ORCID 0000-0003-0687-2910
Jiehui LiNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.ORCID 0000-0002-7812-8878
Robert M BrackbillNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.ORCID 0000-0003-0518-0330
Mark R FarfelNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.ORCID 0000-0002-9952-9937
James E ConeNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.ORCID 0000-0003-2145-1348
Amy R KahnNew York State Department of Health, Bureau of Cancer Epidemiology, Albany, New York, USA.ORCID 0000-0002-1025-6312
Baozhen QiaoNew York State Department of Health, Bureau of Cancer Epidemiology, Albany, New York, USA.ORCID 0000-0002-8407-7835
Maria J SchymuraNew York State Department of Health, Bureau of Cancer Epidemiology, Albany, New York, USA.ORCID 0000-0003-0587-8667
Mayris P WebberFire Department of the City of New York (FDNY), Brooklyn, New York, USA.ORCID 0000-0002-8322-4573
Christopher R DasaroDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-9924-195X
Roberto G LucchiniDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-9723-0237
Andrew C ToddDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0001-7864-009X
David J PrezantDepartment of Medicine, Montefiore Medical Center, New York, New York, USA.ORCID 0000-0001-9562-0330
Charles B HallDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0001-9982-8120
Paolo BoffettaDepartment of Hematology and Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, New York, USA.ORCID 0000-0002-3811-2791

Funding

Extension of the World Trade Center RegistryU50OH009739 · OH · NEW YORK CITY HEALTH/MENTAL HYGIENE · PI FARFEL, MARK R · 2009 to 2025
$120.0M
WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2M
WORLD TRADE CENTER REGISTRYU50TS272750 · TS · NEW YORK CITY HEALTH/MENTAL HYGIENE · PI FARFEL, MARK R · 2005 to 2008
$12.3M
Mortality among WTC rescue and recovery workersU01OH011480 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOFFETTA, PAOLO, HALL, CHARLES B · 2017 to 2020
$2.4M
Incidence, Latency, and Survival of Cancer Following World Trade Center ExposureU01OH011315 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BOFFETTA, PAOLO, HALL, CHARLES B · 2016 to 2018
$1.4M
Incidence, Latency, and Survival of Cancer Following World Trade Center ExposureU01OH011932 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI HALL, CHARLES B · 2019 to 2019
$1.1M
Detection and Incidence of Thyroid Cancer among Three Cohorts of WTC-Exposed Rescue and Recovery WorkersU01OH011931 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ZEIG-OWENS, RACHEL · 2019 to 2019
$555k
Detection and Incidence of Thyroid Cancer among Three Cohorts of WTC-Exposed Rescue and Recovery WorkersU01OH011681 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ZEIG-OWENS, RACHEL · 2018 to 2018
$350k
ACL HHS U01OH011315ACL HHS U50OH009739ATSDR CDC HHS U50/ATU272750ATSDR CDC HHS U50 TS272750CDC HHS 6NU58DP006309NCI NIH HHS 75N91018D00005 (Task Order 75N91018F00001)NCI NIH HHS P30 CA013330NIOSH CDC HHS 200-2011-39378NIOSH CDC HHS 200-2011-39383, 200-2017-93325NIOSH CDC HHS 200-2017-93326NIOSH CDC HHS U01 OH011315NIOSH CDC HHS U01OH011315NIOSH CDC HHS U01 OH011480NIOSH CDC HHS U01 OH011681NIOSH CDC HHS U01 OH011931NIOSH CDC HHS U01 OH011932NIOSH CDC HHS U50 OH009739NIOSH CDC HHS U50/OH009739
6 · The paper itself

Abstract

backgroundWorld Trade Center (WTC)-exposed responders may be eligible to receive no-cost medical monitoring and treatment for certified conditions, including cancer. The survival of responders with cancer has not previously been investigated.

methodsThis study compared the estimated relative survival of WTC-exposed responders who developed cancer while enrolled in two WTC medical monitoring and treatment programs in New York City (WTC-MMTP responders) and WTC-exposed responders not enrolled (WTC-non-MMTP responders) to non-responders from New York State (NYS-non-responders), all restricted to the 11-southernmost NYS counties, where most responders resided. Parametric survival models estimated cancer-specific and all-cause mortality. Follow-up ended at death or on December 31, 2016.

resultsFrom January 1, 2005 to December 31, 2016, there were 2,037 cancer cases and 303 deaths (248 cancer-related deaths) among WTC-MMTP responders, 564 cancer cases, and 143 deaths (106 cancer-related deaths) among WTC-non-MMTP responders, and 574,075 cancer cases and 224,040 deaths (158,645 cancer-related deaths) among the NYS-non-responder population. Comparing WTC-MMTP responders with NYS-non-responders, the cancer-specific mortality hazard ratio (HR) was 0.72 (95% confidence interval [CI] = 0.64-0.82), and all-cause mortality HR was 0.64 (95% CI = 0.58-0.72). The cancer-specific HR was 0.94 (95% CI = 0.78-1.14), and all-cause mortality HR was 0.93 (95% CI = 0.79-1.10) comparing WTC-non-MMTP responders to the NYS-non-responder population.

conclusionsWTC-MMTP responders had lower mortality compared with NYS-non-responders, after controlling for demographic factors and temporal trends. There may be survival benefits from no-out-of-pocket-cost medical care which could have important implications for healthcare policy, however, other occupational and socioeconomic factors could have contributed to some of the observed survival advantage.

Indexed as

Emergency RespondersNeoplasmsSeptember 11 Terrorist AttacksCohort StudiesHumansNew York CityProportional Hazards Modelscancermedical monitoring and treatmentmortalityrescue/recovery workWorld Trade Center

Identifiers

PMID34288025
PMCPMC8515734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.