Evidence map›Paper›PMID 34287966›Full record

ArticleMedical physics2021

Assessment of multi-energy inter-pixel coincidence counters for photon-counting detectors at the presence of charge sharing and pulse pileup: A simulation study.

Katsuyuki Taguchi, Jan S Iwanczyk

Abstract read
In one paragraph

Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. The potential of scintillator-based photon counting detectors: evaluation using Monte Carlo simulations.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  4. Imaging performance of a LaBrMedical physics · 2025
    Article
  5. Number of energy windows for photon counting detectors: is more actually more?Journal of medical imaging (Bellingham, Wash.) · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. [A comprehensive review on photon-counting computed tomography: Principles, technical hurdles and analysis of clinical applications].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Katsuyuki TaguchiThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jan S IwanczykIndependent consultant, Los Angeles, CA, USA.

Funding

Quasi-ideal photon counting x-ray CT with multi-energy inter-pixel coincidence counter (MEICC)R21EB029739 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI TAGUCHI, KATSUYUKI · 2020 to 2021
$436k
NIBIB NIH HHS R21 EB029739
6 · The paper itself

Abstract

purposeSpectral distortion due to charge sharing (CS) and pulse pileup (PP) in photon-counting detectors (PCDs) degrades the quality of PCD data. We recently proposed multi-energy inter-pixel coincidence counters (MEICC) that provided spectral cross-talk information related to CS. When PP was absent, the normalized Cramér-Rao lower bounds (nCRLBs) of 225-µm pixel PCDs with MEICC was comparable to those of 450-µm pixel PCD without MEICC. The aim of this study was to assess the performance of PCDs with MEICC in the presence of both CS and PP using computer simulations.

methodsAn in-house Monte Carlo program was modified to incorporate the following four temporal elements: (1) A pulse shape with a pulse duration of 20 ns, (2) delays of up to 10 ns in anode arrival times when photons were incident on pixel boundaries, (3) offsets proportional to a vertical separation between the primary and secondary charge clouds at the rate of ±4 ns per ±100 µm, and (4) a stochastic fluctuation of anode arrival times for all of the charge clouds with a standard deviation of 2 ns. We assessed the performance of five PCDs, (a)-(f), for three spectral tasks, (A)-(C): (a) The conventional PCD, (b) a PCD with MEICC, (c) a PCD with one coincidence counter (1CC), (d) a PCD with a 3 × 3 analog charge summing scheme (ACS), and (e) a PCD with a 3 × 3 digital count summing scheme (DCS); (A) conventional CT imaging with water (i.e., linear attenuation coefficient maps), (B) water-bone material decomposition, and (C) K-edge imaging with tungsten. The tube current was changed from 1 mA to 1000 mA and the nCRLB was assessed.

resultsThe recorded count rate curves were fitted by the non-paralyzable detection model with the effective deadtime parameter. The best fit was achieved by 25.8 ns for the conventional PCD, 18.6 ns for MEICC and 1CC, 140.5 ns for ACS, and 209.0 ns for DCS. The nCRLBs were strongly dependent on count rates. MEICC provided the best nCRLBs for all of the imaging tasks over the count rate range investigated except for a few conditions such as K-edge imaging at 1 mA. PP decreased the merit of MEICC over the conventional PCD in addressing CS. Nonetheless, MEICC consistently provided better nCRLBs than the conventional PCD did. The nCRLBs of MEICC were in the range of 49-58% of those of the conventional PCD for K-edge imaging, 45-76% for water-bone material decomposition, and 81-88% for the conventional CT imaging (i.e., linear attenuation coefficient maps). ACS provided better nCRLBs than the conventional PCD did only when the effect of PP was minor (e.g., when the counting efficiency of the conventional PCD was higher than 0.95 with the tube current of up to 100 mA).

conclusionBesides a few cases, MEICC provides the best nCRLBs for all of the tasks at all of the count rates. ACS and DCS provide better nCRLBs than the conventional PCD does only when count rates are very low.

Indexed as

PhotonsComputer SimulationMonte Carlo Methodcharge sharingphoton-counting CTphoton-counting detectorspulse pileup

Identifiers

PMID34287966
PMCPMC9942613

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.