ArticleAnnals of nuclear medicine2021
Optimization of injection dose in
Article in Annals of nuclear medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Phase I/IIa clinical trial ofAnnals of nuclear medicine · 2026Article
- Bone remodeling, not inflammation, as the predominant pathology in modic type 1 lesions of the lumbar spine.Pain medicine (Malden, Mass.) · 2026Article
- Evaluation of the feasibility of anomaly detection for dose management in PET examinations.Annals of nuclear medicine · 2025Article
- Article
- Synthesis, preclinical assessment, and first-in-human study of [European journal of nuclear medicine and molecular imaging · 2025Article
- Predictive role of [EJNMMI reports · 2024Article
- LowQuantitative imaging in medicine and surgery · 2024Article
- Local Diagnostic Reference Levels for Common Adult Computed Tomography Procedures in Addis Ababa.Dose-response : a publication of International Hormesis SocietyArticle
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11 authors.
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Abstract
objectiveRecently, the national diagnostic reference levels (DRLs) in Japan were revised as the DRLs 2020, wherein the body weight-based injection dose optimization in positron emission tomography/computed tomography using
methodsA total of 1,231 patients were enrolled in this study. A fixed injection dose of 240 MBq was administered to 624 patients, and a dose adjusted to 3.7 MBq/kg body weight was given to 607 patients. The patients with body weight-based injection doses were further divided according to body weight: group 1 (≤ 49 kg), group 2 (50-59 kg), group 3 (60-69 kg), and group 4 (≥ 70 kg). The effective radiation dose of FDG PET was calculated using the conversion factor of 0.019 mSv/MBq, per the International Commission on Radiological Protection publication 106. Image quality was assessed using noise equivalent count density (NEC
resultsThe body weight-based injection dose optimization significantly decreased the effective dose by 11%, from 4.54 ± 0.1 mSv to 4.05 ± 0.8 mSv (p < 0.001). Image quality evaluated by NEC
conclusionBody weight-based FDG injection dose optimization contributed to not only the reduction of effective dose but also the improvement of image quality in patients weighing between 50 and 69 kg.
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