Evidence map›Paper›PMID 34287757›Full record

Observational studyAIDS and behavior2022

A Cross-Sectional Study to Evaluate the Effects of Age and Duration of HIV Infection on Anxiety and Depression in Cisgender Men.

Sara Gianella, Rowan Saloner, Genevieve Curtin, Susan J Little, Anne Heaton, Jessica L Montoya, Scott L Letendre, María J Marquine, Dilip V Jeste, David J Moore

Erratum issuedOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sara GianellaDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA. gianella@ucsd.edu.ORCID http://orcid.org/0000-0002-9927-0849
Rowan SalonerDepartment of Psychiatry, University of California San Diego, La Jolla, USA.
Genevieve CurtinDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA.
Susan J LittleDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA.
Anne HeatonDepartment of Psychiatry, University of California San Diego, La Jolla, USA.
Jessica L MontoyaDepartment of Psychiatry, University of California San Diego, La Jolla, USA.
Scott L LetendreDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, 9500 Gilman Drive MC 0679, La Jolla, CA, 92093-0679, USA.
María J MarquineDivision of Geriatrics, Gerontology and Palliative Care, University of California, La Jolla, USA.
Dilip V JesteDepartment of Psychiatry, University of California San Diego, La Jolla, USA.
David J MooreDepartment of Psychiatry, University of California San Diego, La Jolla, USA.
University of California San Diego · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAVID J MOORE · 2001 to 2026
$50.4M
Primary Infection Resource Consortium (PIRC)R24AI106039 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2013 to 2021
$23.1M
Revealing Reservoirs during Rebound (R3)P01AI131385 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEIBEL, NADIR · 2017 to 2021
$8.7M
Multi-Dimensional Successful Aging Among HIV-Infected AdultsR01MH099987 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JESTE, DILIP V., MOORE, DAVID J · 2013 to 2019
$3.8M
Mechanisms of CMV Replication on HIV PersistenceR01AI147821 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GIANELLA WEIBEL, SARA · 2020 to 2024
$3.2M
The HIV-associated Opioid Micro-Environment (HOME) ProjectDP2DA051915 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GIANELLA WEIBEL, SARA · 2020 to 2020
$2.4M
An integrated incentive-based treatment to optimize HIV treatment engagement among persons who use methamphetamineK23DA051324 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MONTOYA, JESSICA LYNETTE · 2021 to 2025
$1.0M
Effect of Declining Sex Hormones on HIV persistence in HIV Infected Women on ARTR21HD094646 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GIANELLA WEIBEL, SARA · 2017 to 2018
$441k
Effect of Sex Hormones on HIV persistenceR21AI134295 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GIANELLA WEIBEL, SARA · 2017 to 2018
$426k
NCATS NIH HHS UL1 TR001442NIAID NIH HHS P01 AI131385NIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI036214NIAID NIH HHS R01 AI147821NIAID NIH HHS R21 AI134295NIAID NIH HHS R24 AI106039NIA NIH HHS F31 AG064989NIA NIH HHS MH099987NICHD NIH HHS R21 HD094646NIDA NIH HHS DA051915NIDA NIH HHS DP2 DA051915NIDA NIH HHS K23 DA051324NIMH NIH HHS MH062512NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH099987
6 · The paper itself

Abstract

This observational cross-sectional study of 152 people with HIV (PWH) examined the effects of age and estimated duration of HIV infection (EDI) on depressive and anxiety symptoms. All participants were cisgender men and completed the Profile of Moods State (POMS), a self-report inventory of current (i.e., past week) mood states. Overall, study results confirmed higher levels of anxiety and depression in PWH compared to individuals without HIV. Age group (< 50 or ≥ 50 years) moderated the effect of EDI (< 3 or ≥ 3 years) on mood disturbance. Specifically, younger PWH with early diagnosed infection exhibited the highest levels of depression and anxiety, whereas depression and anxiety were attenuated in older PWH with early infection such that their POMS scores did not significantly differ from the HIV-negative and chronically HIV-infected groups. Despite the small sample size and other important limitations in our study design, our preliminary findings confirm previous observations that older people may have some adaptive ability to better handle the acute psychological stressors associated with recent HIV infection.

Indexed as

HIV InfectionsAgedAnxietyAnxiety DisordersCross-Sectional StudiesDepressionHumansMaleMiddle AgedAnxietyDepressionDuration of HIV infectionHIV

Identifiers

PMID34287757
PMCPMC8294268
OpenAlexW3184716361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.