Evidence map›Paper›PMID 34287568›Full record

ArticleArquivos brasileiros de cardiologia2021

Association of Body Composition with Arterial Stiffness in Long-lived People.

Flávia Veríssimo Melo E Silva, Franciellen Bruschi Almonfrey, Cinthia Medice Nishide de Freitas, Flávia Kurebayashi Fonte, Mariana Bellaguarda de Castro Sepulvida, Clineu de Mello Almada-Filho, Maysa Seabra Cendoroglo, Egli Belinazzi Quadrado, Celso Amodeo, Rui Povoa and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Article
  7. Waist Circumference: A Parameter of Vascular Health.Arquivos brasileiros de cardiologia · 2022
    Article
  8. Article
  9. Vascular Stiffness in Aging and Disease.Frontiers in physiology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Flávia Veríssimo Melo E SilvaUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.
Franciellen Bruschi AlmonfreyUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.
Cinthia Medice Nishide de FreitasUniversidade Estadual de Campinas (UNICAMP), Campinas, SP - Brasil.
Flávia Kurebayashi FonteUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.
Mariana Bellaguarda de Castro SepulvidaUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.
Clineu de Mello Almada-FilhoUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.
Maysa Seabra CendorogloUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.
Egli Belinazzi QuadradoUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.
Celso AmodeoUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.ORCID 0000-0002-8523-760X
Rui PovoaUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.ORCID 0000-0002-4295-9151
Roberto Dischinger MirandaUniversidade Federal de São Paulo - Escola Paulista de Medicina (Unifesp- EPM), São Paulo, SP - Brasil.ORCID 0000-0002-1582-7268
Universidade Federal de São Paulo · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArterial stiffness, obesity and sarcopenia correlate with each other and with cardiac outcomes in younger adults. However, there is little evidence of the association between body composition and markers of central arteries stiffness in long-lived people.

objectiveTo evaluate the relationship between arterial stiffness and body composition in functionally independent long-lived individuals.

methodsThis is a cross-sectional analysis of the association between markers of arterial stiffness and body composition among participants in a longitudinal cohort of elderly individuals aged 80 years or older who were functionally independent and lived in the community . Body composition measurements were performed using dual energy X-ray absorptiometry (DEXA) and central circulation parameters (CCP) obtained by a non-invasive oscillometric method through the Mobil-O-Graph 24h PWA Monitor® device. The central parameters evaluated were: pulse wave velocity (PWV), augmentation Index (AIx), pulse pressure amplification index (PPAi) and central pulse pressure (cPP). These were correlated to total lean mass (LM) and appendicular lean mass (aLM), body fat percentage, and Baumgartner's Index (BI). The level of significance was set at 5% for all tests.

resultsData from 124 elderly people with a mean age of 87.1 years (SD ± 4.3 years) were analyzed, with 74.2% of women and 57.3% of white. There was a statistically significant inverse correlation of AIx with LM (r = -0.391, p <0.001), aLM (r = -0.378, p <0.001), and BI (r = -0.258, p = 0.004). Also, cPP had an inversely proportional association with LM (r = -0.268, p = 0.003), aLM (r = -0.288, p = 0.001), and BI (r = -0.265, p = 0.003). When assessing the relationship between fat mass and CCP, a statistically significant direct relationship was observed only between AIx and body fat percentage (r = 0.197, p = 0.029).

conclusionIn long-lived people, body fat percentage is directly associated with arterial stiffness and inversely associated with the amount of LM. These findings may be associated with increased cardiovascular risk.

Indexed as

Vascular StiffnessAdultAgedAged, 80 and overBlood PressureBody CompositionCross-Sectional StudiesFemaleHumansPulse Wave Analysis

Identifiers

PMID34287568
PMCPMC8462957
OpenAlexW3176628651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.