Evidence map›Paper›PMID 34287384›Full record

ArticleTropical medicine and infectious disease2021

High Effectiveness of SARS-CoV-2 Vaccines in Reducing COVID-19-Related Deaths in over 75-Year-Olds, Ceará State, Brazil.

Carlos Henrique Alencar, Luciano Pamplona de Góes Cavalcanti, Magda Moura de Almeida, Patrícia Pereira Lima Barbosa, Kellyn Kessiene de Sousa Cavalcante, Déborah Nunes de Melo, Bruno Cavalcante Fales de Brito Alves, Jorg Heukelbach

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

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  8. Adverse effect investigation using application software after vaccination against SARS-CoV-2 for healthcare workers.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022
    Article
  9. Article
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  13. COVID-19: Current Challenges and Future Perspectives.Tropical medicine and infectious disease · 2022
    Article
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Carlos Henrique AlencarSchool of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil.ORCID 0000-0003-2967-532X
Luciano Pamplona de Góes CavalcantiSchool of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil.ORCID 0000-0002-3440-1182
Magda Moura de AlmeidaSchool of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil.
Patrícia Pereira Lima BarbosaSchool of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil.ORCID 0000-0003-2863-0787
Kellyn Kessiene de Sousa CavalcanteSchool of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil.
Déborah Nunes de MeloSchool of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil.
Bruno Cavalcante Fales de Brito AlvesChristus University Center, Fortaleza 60190-180, Brazil.ORCID 0000-0002-7056-6726
Jorg HeukelbachSchool of Medicine, Post Graduate Program in Public Health, Federal University of Ceará, Fortaleza 60430-140, Brazil.ORCID 0000-0002-7845-5510
Universidade Federal do Ceará · BRUniversidade Estadual do Ceará · BRUnichristus · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Brazil, the SARS-CoV-2 vaccination program has so far prioritized people over 75 years of age. By the end of March 2021, in Ceará State, a total of 313,328 elderly people had received at least one dose of vaccine (45% Oxford-AstraZeneca/Fiocruz and 55% CoronaVac-Sinovac/Butantan), and 159,970 had received two doses (83% CoronaVac-Sinovac/Butantan and 17% Oxford-AstraZeneca/Fiocruz). After a single dose, there was already a significant reduction in COVID 19-related deaths (protection ratio: 19.31 (95% CI: 18.20-20.48), attributable protection ratio: 94.8%); higher protection ratios were observed after the application of two doses of the vaccine (132.67; 95% CI: 109.88-160.18), with an attributable protection ratio of 99.2%. SARS-CoV-2 vaccines are highly effective in reducing the number of COVID-19-related deaths in over 75-year-olds in Brazil, one of the hardest hit countries by the current pandemic.

Indexed as

COVID-19COVID-19 vaccinesepidemiologymortalitypublic healthSARS-CoV-2

Identifiers

PMID34287384
PMCPMC8293450
OpenAlexW3179871642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.