Evidence map›Paper›PMID 34287351›Full record

ArticleNeurology international2021

Median-to-Ulnar Nerve Communication in Carpal Tunnel Syndrome: An Electrophysiological Study.

Vincenzo Di Stefano, Andrea Gagliardo, Filomena Barbone, Michela Vitale, Laura Ferri, Antonino Lupica, Salvatore Iacono, Antonio Di Muzio, Filippo Brighina

Open access · goldAbstract read
In one paragraph

Article in Neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Nerve anastomoses in the upper limb: an up-to-date meta-analysis.Surgical and radiologic anatomy : SRA · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Vincenzo Di StefanoDepartment of Biomedicine, Neuroscience and Advanced Diagnostic (BIND), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-9805-1655
Andrea GagliardoDepartment of Biomedicine, Neuroscience and Advanced Diagnostic (BIND), University of Palermo, 90127 Palermo, Italy.
Filomena BarboneDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, 66013 Chieti, Italy.
Michela VitaleDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, 66013 Chieti, Italy.
Laura FerriDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, 66013 Chieti, Italy.ORCID 0000-0003-2105-5038
Antonino LupicaDepartment of Biomedicine, Neuroscience and Advanced Diagnostic (BIND), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-1499-9460
Salvatore IaconoDepartment of Biomedicine, Neuroscience and Advanced Diagnostic (BIND), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-0035-5859
Antonio Di MuzioDepartment of Neurology, "SS Annunziata" Hospital, 66100 Chieti, Italy.
Filippo BrighinaDepartment of Biomedicine, Neuroscience and Advanced Diagnostic (BIND), University of Palermo, 90127 Palermo, Italy.
University of Palermo · ITUniversity of Chieti-Pescara · ITOspedale SS. Annunziata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The median-to-ulnar communicating branch (MUC) is an asymptomatic variant of the upper limb innervation that can lead to interpretation errors in routine nerve conduction studies. The diagnosis of carpal tunnel syndrome (CTS) or ulnar nerve lesions can be complicated by the presence of MUC. In this study, we describe electrophysiological features of MUC in CTS patients presenting to our clinic. We enrolled MUB cases from consecutive CTS patients referred to our laboratory between the years 2014 and 2019. MUC was present in 53 limbs (36 patients) from the studied population. MUC was bilateral in 53% of patients. MUC type II was the most common subtype (74%), followed by types III and I; more coexisting MUC types were found in the majority of tested limbs. A positive correlation was demonstrated between the severity of CTS and the presence of positive onset, faster CV, or a double component of the compound muscle action potentials. We emphasize the importance of suspecting the presence of MUC in CTS in the presence of a positive onset or a double component in routine motor conduction studies.

Indexed as

carpal tunnel syndromeMartin-Gruber anastomosismedian nerveneurophysiologyulnar nerveulnar neuropathy at elbow

Identifiers

PMID34287351
PMCPMC8293426
OpenAlexW3182296347

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.