Evidence map›Paper›PMID 34287336›Full record

ArticleMedical sciences (Basel, Switzerland)2021

Reduction in Fatigue Symptoms Following the Administration of Nutritional Supplements in Patients with Multiple Sclerosis.

Pasquale Ferorelli, Francesco Antonelli, Anna Shevchenko, Carlo Mischiati, Manfred Doepp, Stefano Lenzi, Ilaria Borromeo, Giordana Feriotto, Simone Beninati

Open access · goldAbstract read
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Pasquale FerorelliScientific Research Institute "CRSC", 20100 Milan, Italy.
Francesco AntonelliScientific Association "ARSS", 00100 Rome, Italy.
Anna ShevchenkoDepartment of Pharmacology, Kabardine University, 101000 Nalchik, Russia.
Carlo MischiatiDepartment of Neuroscience and Rehabilitation, University of Ferrara, 44100 Ferrara, Italy.ORCID 0000-0002-0029-2205
Manfred DoeppDepartment of Psychology and Sports Science, Giessen Justus, Liebig University Gießen, 35398 Gießen, Germany.ORCID 0000-0002-2493-6773
Stefano LenziDepartment of Health Engineering, Université Européenne de Bruxelles Jean Monnet, Schaerbeek, 1030 Brussels, Belgium.
Ilaria BorromeoDepartment of Physics, University of Tor Vergata, 00100 Rome, Italy.ORCID 0000-0001-5925-4222
Giordana FeriottoDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44100 Ferrara, Italy.
Simone BeninatiDepartment of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00100 Rome, Italy.ORCID 0000-0002-2704-0745
University of Ferrara · ITUniversity of Rome Tor Vergata · ITAmbiente Risorse Sviluppo · ITIstituto Scientifico Italiano Colonna Vertebrale · ITJustus-Liebig-Universität Gießen · DEKabardino-Balkarian State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances in immune-modulatory drugs, pharmacological therapies have been proven ineffective in severe presentations of multiple sclerosis (MS), including secondary progressive MS. At present, therapeutic interventions' performance is primarily focused on ameliorating symptoms to improve the patient's quality of life (QOL). Among complementary treatments, nutrition has been considered a decisive factor to control symptoms and enhance the wellness of MS patients. Although no special diets are associated with MS, the impact of diet and dietary supplements on the course of progressive forms of the disease has been studied during the last few years. Fatigue is among the most common and disabling symptoms reported by MS patients. Fatigue has been defined in the Multiple Sclerosis Council for Clinical Practice Guidelines (MSCCPG, 1998) as a "subjective lack of physical and/or mental energy that the individual perceives as an interference with habitual and desired activities". This study aimed to compare the psychometric functioning of the "Fatigue Severity Scale" (FSS) and the "Modified Fatigue Impact Scale" (MFIS) in our sample of people with MS. Specifically, during chronic treatment, the change in these two parameters with two vitamin-rich dietary supplements (Citozym

Indexed as

Multiple SclerosisDietary SupplementsFatigueHumansMultiple Sclerosis, Chronic ProgressiveQuality of Lifedietary supplementsfatiguemultiple sclerosisQOLvitamins

Identifiers

PMID34287336
PMCPMC8293375
OpenAlexW3185558155

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.