Evidence map›Paper›PMID 34287226›Full record

ArticleAudiology research2021

Sudden Sensorineural Hearing Loss in Mild COVID-19: Case Series and Analysis of the Literature.

Filippo Ricciardiello, Davide Pisani, Pasquale Viola, Elisabetta Cristiano, Alfonso Scarpa, Antonio Giannone, Giuseppe Longo, Giuseppe Russo, Marco Bocchetti, Ciro Coppola and 3 more

Open access · goldAbstract read
In one paragraph

Article in Audiology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Efficacy and safety ofPharmaceutical biology · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. A Prospective Study on Post Covid Sudden Onset Sensory Neural Hearing Loss and Its Recovery.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Filippo RicciardielloENT Department, AORN Cardarelli, 80131 Napoli, Italy.
Davide PisaniUnit of Audiology, Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0001-7486-0140
Pasquale ViolaUnit of Audiology, Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-2352-1146
Elisabetta CristianoENT Department, AORN Cardarelli, 80131 Napoli, Italy.
Alfonso ScarpaDepartment of Medicine and Surgery, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0001-9219-6175
Antonio GiannoneENT Department, AORN Cardarelli, 80131 Napoli, Italy.
Giuseppe LongoAORN Cardarelli, 80131 Napoli, Italy.
Giuseppe RussoHealth Management, AORN Cardarelli, 80131 Napoli, Italy.
Marco BocchettiBiogem Scarl, Molecular Oncology and Precision Medicine Laboratory, 83031 Irpino, Italy.ORCID 0000-0002-2143-6669
Ciro CoppolaHealth Management, AORN Cardarelli, 80131 Napoli, Italy.
Marco PerrellaAnesthesiology and Reanimation Department, AORN Cardarelli, 80100 Napoli, Italy.
Flavia OlivaENT Department, AORN Cardarelli, 80131 Napoli, Italy.
Giuseppe ChiarellaUnit of Audiology, Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-9829-2229
Ospedale Antonio Cardarelli · ITMagna Graecia University · ITBiogem · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is growing evidence of otoneurological involvement of SARS-CoV-2, such as tinnitus and balance disorders and smell and taste disorders, but HL in COVID-19 patients has still been marginally studied. Investigating the role of SARS-CoV-2 as an aetiological factor of Sudden Sensorineural Hearing Loss (SSNHL) may offer the opportunity to address treatment strategies to maximize clinical recovery and avoid side effects. METHODS AND

resultsFor this purpose, we will present case studies of five patients who experienced SSNHL during COVID-19. Patients were selected from COVID-19 positive adult subjects with mild clinical presentation, admitted to the outpatient Ear Nose and Throat Department of Cardarelli Hospital due to the onset of SSNHL during the infection. All underwent a complete audio-vestibular investigation before and after SSNHL treatment protocol. Each patient is described with a detailed analysis.

conclusionsSSNHL could be an occasional symptom of COVID-19, even in mild manifestations of the disease. Our experience leads us to underline the value of promptly recognizing and addressing this and other uncommon symptoms, giving patients the opportunity to receive early treatment.

Indexed as

coronavirusCOVID-19hearing lossSARS-CoV-2SSNHLsudden sensorineural hearing losstinnitustreatmentvertigo

Identifiers

PMID34287226
PMCPMC8293051
OpenAlexW3176269245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.