Evidence map›Paper›PMID 34287055›Full record

ArticleMicrobiology spectrum2021

Investigating the Roles of Listeria monocytogenes Peroxidases in Growth and Virulence.

Monica R Cesinger, Nicole H Schwardt, Cortney R Halsey, Maureen K Thomason, Michelle L Reniere

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. The roles of theJournal of bacteriology · 2026
    Article
  3. Article
  4. Biodiversity of the antimicrobial potential ofFrontiers in microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Monica R Cesinger *Department of Microbiology, University of Washingtongrid.34477.33grid.471394.c School of Medicine, Seattle, Washington, USA.
Nicole H Schwardt *Department of Microbiology, University of Washingtongrid.34477.33grid.471394.c School of Medicine, Seattle, Washington, USA.
Cortney R HalseyDepartment of Microbiology, University of Washingtongrid.34477.33grid.471394.c School of Medicine, Seattle, Washington, USA.
Maureen K ThomasonDepartment of Microbiology, University of Washingtongrid.34477.33grid.471394.c School of Medicine, Seattle, Washington, USA.
Michelle L ReniereDepartment of Microbiology, University of Washingtongrid.34477.33grid.471394.c School of Medicine, Seattle, Washington, USA.ORCID 0000-0002-0770-7784
University of Washington · US

Funding

The role of redox sensing in Listeria monocytogenes pathogenesisR01AI132356 · NIAID · UNIVERSITY OF WASHINGTON · PI Joshua Woodward · 2017 to 2026
$4.4M
INTERDISCIPLINARY PROGRAM IN BACTERIAL PATHOGENESIST32AI055396 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2003 to 2019
$2.8M
NIAID NIH HHS R01 AI132356NIAID NIH HHS T32 AI055396
6 · The paper itself

Abstract

Bacteria have necessarily evolved a protective arsenal of proteins to contend with peroxides and other reactive oxygen species generated in aerobic environments. Listeria monocytogenes encounters an onslaught of peroxide both in the environment and during infection of the mammalian host, where it is the causative agent of the foodborne illness listeriosis. Despite the importance of peroxide for the immune response to bacterial infection, the strategy by which L. monocytogenes protects against peroxide toxicity has yet to be illuminated. Here, we investigated the expression and essentiality of all the peroxidase-encoding genes during L. monocytogenes growth

Indexed as

AnimalsBacterial ProteinsDisease Models, AnimalGene Expression Regulation, BacterialListeria monocytogenesListeriosisMacrophagesMiceMice, Inbred C57BLOxidative StressPeroxidasesVirulenceVirulence FactorsBacterial ProteinsPeroxidasesVirulence Factorshemeoxidative stressperoxideredox signalingvirulence

Identifiers

PMID34287055
PMCPMC8552690
OpenAlexW3155628962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.