Evidence map›Paper›PMID 34287050›Full record

ArticleJournal of virology2021

Development of a Novel

Michelle E Wong, Chad J Johnson, Anna C Hearps, Anthony Jaworowski

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
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  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. HIV Latency in Myeloid Cells: Challenges for a Cure.Pathogens (Basel, Switzerland) · 2022
    Review
  14. Review
  15. Choosing a cellular model to study SARS-CoV-2.Frontiers in cellular and infection microbiology · 2022
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Michelle E WongLife Sciences Discipline, Burnet Institute, Melbourne, Australia.
Chad J JohnsonBioimaging Platform, La Trobe University, Melbourne, Australia.
Anna C Hearps *Life Sciences Discipline, Burnet Institute, Melbourne, Australia.ORCID 0000-0002-8492-9815
Anthony Jaworowski *Department of Infectious Diseases, Monash University, Melbourne, Australia.ORCID 0000-0002-3844-805X
Burnet Institute · AULa Trobe University · AUMonash University · AU

Funding

Department of Health, Australian Government | National Health and Medical Research Council (NHMRC) 1161708
6 · The paper itself

Abstract

Latent HIV reservoirs persist in people living with HIV despite effective antiretroviral therapy and contribute to rebound viremia upon treatment interruption. Macrophages are an important reservoir cell type, but analysis of agents that modulate latency in macrophages is limited by lack of appropriate

Indexed as

Transcription, GeneticVirus ActivationBryostatinsCytokinesHIV-1HumansMacrophagesPanobinostatT-LymphocytesVirus LatencyVirus ReplicationVorinostatBryostatinsCytokinesPanobinostatVorinostatHIV latencyhuman immunodeficiency viruslatency-reversing agentmacrophages

Identifiers

PMID34287050
PMCPMC8428379
OpenAlexW3183184137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.