Evidence map›Paper›PMID 34286967›Full record

ArticleJournal of the American Chemical Society2021

Aptamer-Modified Cu

Yu Ouyang, Yonatan Biniuri, Michael Fadeev, Pu Zhang, Raanan Carmieli, Margarita Vázquez-González, Itamar Willner

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 122 citations in OpenAlex.

  1. Article
  2. Review
  3. Can nanozymes achieve more than enzymes?Nature reviews. Materials · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Nucleic Acid-Modified Nanoparticles for Cancer Therapeutic Applications.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yu OuyangThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Yonatan BiniuriThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Michael FadeevThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Pu ZhangThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Raanan CarmieliDepartment of Chemical Research Support, Weizmann Institute of Science, Rehovot 76100, Israel.ORCID 0000-0003-4418-916X
Margarita Vázquez-GonzálezThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Itamar WillnerThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0001-9710-9077
Hebrew University of Jerusalem · ILWeizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The covalent linkage of aptamer binding sites to nanoparticle nanozymes is introduced as a versatile method to improve the catalytic activity of nanozymes by concentrating the reaction substrates at the catalytic nanozyme core, thereby emulating the binding and catalytic active-site functions of native enzymes. The concept is exemplified with the synthesis of Cu

Indexed as

Aptamers, NucleotideCarbonCatalysisCopperDopamineMolecular StructureOxidation-ReductionQuantum DotsTyrosineAptamers, NucleotideCarbonCopperDopaminetyrosinamideTyrosine

Identifiers

PMID34286967
PMCPMC8856595
OpenAlexW3183568930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.