ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
The Prognostic Value of a Derived Neutrophil-Lymphocyte Ratio in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.
Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Predictive role of neutrophil-to-lymphocyte ratio in metabolic syndrome: Meta-analysis of 70,937 individuals.BMC endocrine disorders · 2024Pooled it
- Systemic immune-inflammation index as a novel predictor of major adverse cardiovascular events in patients undergoing percutaneous coronary intervention: a meta-analysis of cohort studies.BMC cardiovascular disorders · 2024Pooled it
- A Nomogram Based on the Castelli Risk Index for Predicting Prognosis in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: A Cohort Study.Immunity, inflammation and disease · 2026Article
- Prognostic Value of Systemic Immune-Inflammation Index (SII) in Hospital Readmission Following Acute Myocardial Infarction: A Four-Year Analysis.Cardiology research and practice · 2026Article
- Systemic immune-inflammation index and systemic inflammation response index as predictors of mortality in participants with and without cancer.The Journal of international medical research · 2026Article
- Beyond Conventional Blood Parameters: Novel Hematologic Indices for Interpretable Artificial Intelligence in Acute Myocardial Infarction.Journal of clinical practice and research · 2025Article
- The complex inflammatory indexes predict the prognostic risk for patients with acute coronary syndrome undergoing percutaneous coronary intervention.BMC immunology · 2025Article
- Association of high-sensitivity C-reactive protein and hematologic-inflammatory indices with risk of cardiovascular diseases: a population-based study with partial least squares structural equation modeling approach.Molecular and cellular biochemistry · 2025Article
- The Complex Inflammatory and Nutritional Indices to Predict Prognostic Risk for Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.Immunity, inflammation and disease · 2025Article
- Updated focused review of hematological, inflammatory, and lipid biomarkers in acute coronary syndrome.Archives of medical science : AMS · 2025Article
- Association of systemic immune-inflammatory index with in-stent restenosis in patients with and without diabetes mellitus.Frontiers in cardiovascular medicine · 2025Article
- Association of the derived neutrophil-to-lymphocyte ratio with cardiovascular and all-cause mortality.PloS one · 2025Article
- Inflammation-related biomarkers for intracardiac thrombosis in acute myocardial infarction: predictive value and mechanistic implications of NLR and LDL-C.Frontiers in medicine · 2025Article
- An inflammatory prognostic scoring system to predict the risk for adults with acute coronary syndrome undergoing percutaneous coronary intervention.BMC cardiovascular disorders · 2024Article
- The Prognostic Role of the Neutrophil-to-Lymphocytes Ratio in the Most Frequent Cardiovascular Diseases: An Update.Life (Basel, Switzerland) · 2024Review
- Curcumin-rich curry consumption and life expectancy: Singapore longitudinal ageing study.GeroScience · 2024Article
- Correlations Between Acute Coronary Syndrome and Novel Inflammatory Markers (Systemic Immune-Inflammation Index, Systemic Inflammation Response Index, and Aggregate Index of Systemic Inflammation) in Patients with and without Diabetes or Prediabetes.Journal of inflammation research · 2024Article
- Inflammatory Hematological Indices, Cardiovascular Disease and Mortality: A Narrative Review.Arquivos brasileiros de cardiologia · 2024Review
- Association of systemic immune-inflammation index with insulin resistance and prediabetes: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Association between systemic immune-inflammation index and metabolic syndrome and its components: results from the National Health and Nutrition Examination Survey 2011-2016.Journal of translational medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The systemic immune-inflammatory index (SII) and derived neutrophil-lymphocyte ratio (dNLR) are novel indexes that simultaneously reflect the host inflammatory and immune status and have prognostic value in some cancers. SII was associated with major cardiovascular events in coronary artery disease patients who received percutaneous coronary intervention (PCI). However, dNLR correlations with clinical outcomes in acute coronary syndrome (ACS) patients undergoing PCI remain unclear. This study aimed to elucidate the predictive values of SII and dNLR on the long-term prognosis of patients with ACS undergoing PCI. In total, 1,553 ACS patients undergoing PCI were consecutively enrolled from January 2016 to December 2018. The subjects were divided into high and low SII and dNLR groups for comparison (high vs. low). The SII and dNLR cutoff values for predicting major adverse cardiovascular events (MACE) were calculated using receiver operating characteristic curves, and Kaplan-Meier curves and Cox regression models were used for survival analyses. The endpoint was a MACE, which included all-cause mortality and rehospitalization for severe heart failure during follow-up. The Kaplan-Meier curves showed that a higher SII or dNLR value was associated with a higher risk of MACE (all
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.