ReviewAmerican journal of clinical dermatology2021
Primary Localized Cutaneous Amyloidosis of Keratinocyte Origin: An Update with Emphasis on Atypical Clinical Variants.
Review in American journal of clinical dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- A systematic review of procedural treatment for primary localized cutaneous amyloidosis: focus on efficacy, safety, treatment durability in comparison and combination.Lasers in medical science · 2025Pooled it
- The effect of topical tranexamic acid with micro-needling and micro-needling alone in treatment of macular amyloidosis.Journal of cosmetic dermatology · 2024Trial
- Destroy and reconstruct: A microneedle platform for combined NIR-II photothermal therapy and asiaticoside-mediated tissue regeneration in cutaneous amyloidosis.Materials today. Bio · 2026Article
- Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Disseminated superficial porokeratosis with dermal amyloid deposits: A case report and review of the literature.The Journal of international medical research · 2026Review
- Case Report: Ivarmacitinib in the treatment of refractory primary cutaneous amyloidosis.Frontiers in medicine · 2026Article
- Familial Amyloidosis Cutis Dyschromica with GPNMB mutation: A Case Report and Literature Review.Acta dermato-venereologica · 2025Article
- Histopathological Insights into Primary Localized Cutaneous Amyloidosis: A Case Series.Cureus · 2025Article
- Periprosthetic joint infection of the knee complicated by primary localized cutaneous amyloidosis: a case report.Frontiers in medicine · 2025Article
- Dupilumab for treatment of primary cutaneous amyloidosis in adults: two case reports and literature review.Frontiers in medicine · 2025Article
- Endocrine Perspective of Cutaneous Lichen Amyloidosis:Clinics and practice · 2024Article
- Thyroid Malignancy and Cutaneous Lichen Amyloidosis: Key Points AmidInternational journal of molecular sciences · 2024Review
- Case report: Abrocitinib: a potential therapeutic option for lichen amyloidosis associated with atopic dermatitis.Frontiers in immunology · 2024Article
- Primary Localized Cutaneous Amyloidosis in Central Europe: A Retrospective Monocentric Study on Epidemiology and Therapy.Journal of clinical medicine · 2023Article
- Clinical Characteristics of Lichen Amyloidosis Associated with Atopic Dermatitis: A Single Center, Retrospective Study.Annals of dermatology · 2023Article
- Article
- Dupilumab for treatment of severe atopic dermatitis accompanied by lichenoid amyloidosis in adults: Two case reports.World journal of clinical cases · 2023Article
- Lichen Amyloidosis on the Scalp: A Case Report.Clinical, cosmetic and investigational dermatology · 2022Article
- [Generalized Amyloid Lichen Associated with Primary Biliary Cholangitis: A Case Report].Acta gastroenterologica LatinoamericanaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amyloid is a protein derived from at least 20 different substances. Once misfolded, it results in a group of cutaneous and systemic conditions. Primary localized cutaneous amyloidosis of keratinocyte origin is a very common subtype that can manifest either as lichen or macular amyloidosis, lacking systemic involvement. Lichen amyloidosis often presents as multiple hyperpigmented papules on the lower extremities whereas macular amyloidosis is classically characterized by dark brown rippled macules on the interscapular area. Review of the literature reveals that in addition to the classical presentation of primary localized cutaneous amyloidosis there exists a plethora of various manifestations that can be grouped into either geographic or morphologic categories. This review provides clinicians with the intimate knowledge of these presentations and summarizes the available treatment modalities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.