Evidence map›Paper›PMID 34286398›Full record

Trial reportClinical oral investigations2022

Sealing of cavitated occlusal carious lesions in the dentine of deciduous molars: a two-year randomised controlled clinical trial.

Nicole Marchioro Dos Santos, Soraya Coelho Leal, Daiana Back Gouvea, Caroline Simão Sarti, Julia Toniolo, Matheus Neves, Jonas Almeida Rodrigues

Abstract readRandomized Controlled TrialEquivalence Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nicole Marchioro Dos SantosFederal University of Rio Grande Do Sul, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil.
Soraya Coelho LealUniversity of Brasília, UnB, Brasília, Distrito Federal, Brazil.
Daiana Back GouveaFederal University of Rio Grande Do Sul, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil.
Caroline Simão SartiFederal University of Rio Grande Do Sul, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil.
Julia TonioloFederal University of Rio Grande Do Sul, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil.
Matheus NevesFederal University of Rio Grande Do Sul, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil.
Jonas Almeida RodriguesFederal University of Rio Grande Do Sul, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil. jorodrigues@ufrgs.br.ORCID http://orcid.org/0000-0001-8887-2329
Universidade Federal do Rio Grande do Sul · BRUniversidade de Brasília · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

objectivesThis two-arm, parallel-group, tooth-randomised, controlled noninferiority clinical trial aimed to compare survival rates between the sealing and restoring of cavitated occlusal carious lesions in dentine [International Caries Detection and Assessment System (ICDAS) 5] of deciduous molars using resin-modified glass-ionomer cement (RMGIC) and to assess caries progression radiographically. MATERIALS AND

methodsA total of 68 molars with ICDAS 5 occlusal lesions were randomly allocated into two groups, a sealing group (n = 31), in which RMGIC was placed directly over the carious lesion, and a restoration group (n = 37), in which a restoration with the same material was placed after selective caries removal. During the baseline and follow-up visits, dental caries was registered and caries activity was assessed according to a visuotactile criterion. At baseline, patient caries status (dmf-t) and cavity depth and extent (mesiodistal and buccolingual) were measured before RMGIC placement. An independent and blinded examiner evaluated the treated teeth using the USPHS criteria after one and two years. Standardised interproximal radiographs were taken for caries progression assessments.

resultsDuring the follow-up period, no lesion progression was observed radiographically. After one year (n = 60; 27 sealed and 33 restored) and two years (n = 48; 23 sealed and 25 restored) of follow-up, the treatment success rates were 78.8% and 76.0% in the restoration group and 59.3% and 47.8% in the sealing group, respectively. Multivariate Cox regression showed that lesions smaller than 2 mm in the mesiodistal extent were less prone to fail after one year (p = 0.03). However, survival curves (log-rank test) were statistically significantly different only after two years (p < 0.001).

conclusionsSealing ICDAS 5 occlusal lesions of deciduous molars using RMGIC achieved lower survival rates than restorations. Both sealing and restoration effectively arrested caries progression for two years. Clinical relevance Sealing dentine carious lesions can be effective for treating lesions involving the inner and outer half of the dentine. Ultraconservative treatments can arrest carious lesions presenting obvious cavitation in primary molars.

trial registrationReBEC Register no. RBR-225n35.

Indexed as

Dental CariesDentinGlass Ionomer CementsHumansMolarPit and Fissure SealantsTooth, DeciduousGlass Ionomer CementsPit and Fissure SealantsDeciduous toothDental cariesDentineGlass-ionomer cementSealing

Identifiers

PMID34286398
OpenAlexW3185822262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.