Evidence map›Paper›PMID 34286303›Full record

ArticlePatterns (New York, N.Y.)2021

Structuring clinical text with AI: Old versus new natural language processing techniques evaluated on eight common cardiovascular diseases.

Xianghao Zhan, Marie Humbert-Droz, Pritam Mukherjee, Olivier Gevaert

Abstract read
In one paragraph

Article in Patterns (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xianghao ZhanDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Marie Humbert-DrozStanford Center for Biomedical Informatics Research (BMIR), Department of Medicine, Stanford University, Stanford, CA 94305, USA.
Pritam MukherjeeStanford Center for Biomedical Informatics Research (BMIR), Department of Medicine, Stanford University, Stanford, CA 94305, USA.
Olivier GevaertStanford Center for Biomedical Informatics Research (BMIR), Department of Medicine, Stanford University, Stanford, CA 94305, USA.

Funding

Radiogenomics Framework for Non-Invasive Personalized MedicineR01EB020527 · NIBIB · STANFORD UNIVERSITY · PI GEVAERT, OLIVIER · 2015 to 2018
$2.3M
Radiogenomics framework for non-invasive personalized medicineR56EB020527 · NIBIB · STANFORD UNIVERSITY · PI GEVAERT, OLIVIER · 2019 to 2019
$444k
NIBIB NIH HHS R01 EB020527NIBIB NIH HHS R56 EB020527
6 · The paper itself

Abstract

Free-text clinical notes in electronic health records are more difficult for data mining while the structured diagnostic codes can be missing or erroneous. To improve the quality of diagnostic codes, this work extracts diagnostic codes from free-text notes: five old and new word vectorization methods were used to vectorize Stanford progress notes and predict eight ICD-10 codes of common cardiovascular diseases with logistic regression. The models showed good performance, with TF-IDF as the best vectorization model showing the highest AUROC (0.9499-0.9915) and AUPRC (0.2956-0.8072). The models also showed transferability when tested on MIMIC-III data with AUROC from 0.7952 to 0.9790 and AUPRC from 0.2353 to 0.8084. Model interpretability was shown by the important words with clinical meanings matching each disease. This study shows the feasibility of accurately extracting structured diagnostic codes, imputing missing codes, and correcting erroneous codes from free-text clinical notes for information retrieval and downstream machine-learning applications.

Indexed as

cardiovascular diseaseclinical notesICD-10 codesinterpretabilitynatural language processing

Identifiers

PMID34286303
PMCPMC8276012

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.