Evidence map›Paper›PMID 34286270›Full record

ArticleBrain communications2021

Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer's disease.

Kelly Ceyzériat, Yesica Gloria, Stergios Tsartsalis, Christine Fossey, Thomas Cailly, Frédéric Fabis, Philippe Millet, Benjamin B Tournier

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Glial Cells in Behavioral and Psychological Symptoms of Alzheimer's Disease.International journal of molecular sciences · 2026
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  4. Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kelly CeyzériatDivision of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 1206 Geneva, Switzerland.
Yesica GloriaDivision of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 1206 Geneva, Switzerland.
Stergios TsartsalisDivision of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 1206 Geneva, Switzerland.ORCID https://orcid.org/0000-0002-6565-6313
Christine FosseyNormandie University, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000 Caen, France.ORCID https://orcid.org/0000-0001-7583-1894
Thomas CaillyNormandie University, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000 Caen, France.ORCID https://orcid.org/0000-0002-5262-4494
Frédéric FabisNormandie University, UNICAEN, Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), 14000 Caen, France.
Philippe MilletDivision of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 1206 Geneva, Switzerland.ORCID https://orcid.org/0000-0002-5803-0478
Benjamin B TournierDivision of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 1206 Geneva, Switzerland.ORCID https://orcid.org/0000-0002-8027-7530
Normandie Université · FRUniversity of Geneva · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine pathways alterations are reported in Alzheimer's disease. However, it is difficult in humans to establish when these deficits appear and their impact in the course of Alzheimer's disease. In the TgF344-Alzheimer's disease rat model at the age of 6 months, we showed a reduction in

Indexed as

5HT2A receptorAlzheimer’s diseaseamyloidD2 receptorTSPO

Identifiers

PMID34286270
PMCPMC8287930
OpenAlexW3139009603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.