Evidence map›Paper›PMID 34286177›Full record

ArticleBJR open2021

Calculated relative biological effectiveness (RBE) for initial DNA double-strand breaks (DSB) from flattening filter and flattening filter-free 6 MV X-ray fields.

Hisashi Nakano, Daisuke Kawahara, Satoshi Tanabe, Satoru Utsunomiya, Takeshi Takizawa, Madoka Sakai, Toshimichi Nakano, Atsushi Ohta, Motoki Kaidu, Hiroyuki Ishikawa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJR open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hisashi NakanoDepartment of Radiation Oncology, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan.
Daisuke KawaharaDepartment of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan.
Satoshi TanabeDepartment of Radiation Oncology, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan.
Satoru UtsunomiyaDepartment of Radiological Technology, Niigata University Graduate School of Health Sciences, 2-746 Asahimachi-dori, Chuo-ku, Niigata, Japan.
Takeshi Takizawa
Madoka SakaiDepartment of Radiation Oncology, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan.
Toshimichi NakanoDepartment of Radiation Oncology, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan.
Atsushi OhtaDepartment of Radiation Oncology, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Japan.
Motoki KaiduDepartment of Radiation Oncology, Niigata Neurosurgical Hospital, Niigata, 3057 Yamada, Nishi-ku, Niigata, Japan.
Hiroyuki IshikawaDepartment of Radiation Oncology, Niigata Neurosurgical Hospital, Niigata, 3057 Yamada, Nishi-ku, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe evaluated the radiobiological effectiveness based on the yields of DNA double-strand breaks (DSBs) of field induction with flattening filter (FF) and FF-free (FFF) photon beams.

methodsWe used the particle and heavy ion transport system (PHITS) and a water equivalent phantom (30 × 30 × 30 cm

resultsThe RBE

conclusionsThe out-of-field radiobiological effect of FFF could thus be greater than that of FF since the spreading of the radiation dose out-of-field with FFF could be a concern compared to the FF. ADVANCES IN KNOWLEDGE: The RBE

Identifiers

PMID34286177
PMCPMC8256801

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.