Evidence map›Paper›PMID 34286152›Full record

ReviewInternational journal of bioprinting2021

3D Bioprinting Photo-Crosslinkable Hydrogels for Bone and Cartilage Repair.

Quanjing Mei, Jingdong Rao, Ho Pan Bei, Yaxiong Liu, Xin Zhao

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of bioprinting, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 88 citations in OpenAlex.

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  18. Biomaterials for extrusion-based bioprinting and biomedical applications.Frontiers in bioengineering and biotechnology · 2024
    Review
  19. [Bone/cartilage immunomodulating hydrogels: construction strategies and applications].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Quanjing MeiDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Jingdong RaoDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Ho Pan BeiDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Yaxiong LiuJihua Laboratory, Foshan, Guangdong, China.
Xin ZhaoDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Hong Kong Polytechnic University · HKJi Hua Laboratory · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) bioprinting has become a promising strategy for bone manufacturing, with excellent control over geometry and microarchitectures of the scaffolds. The bioprinting ink for bone and cartilage engineering has thus become the key to developing 3D constructs for bone and cartilage defect repair. Maintaining the balance of cellular viability, drugs or cytokines' function, and mechanical integrity is critical for constructing 3D bone and/or cartilage scaffolds. Photo-crosslinkable hydrogel is one of the most promising materials in tissue engineering; it can respond to light and induce structural or morphological transition. The biocompatibility, easy fabrication, as well as controllable mechanical and degradation properties of photo-crosslinkable hydrogel can meet various requirements of the bone and cartilage scaffolds, which enable it to serve as an effective bio-ink for 3D bioprinting. Here, in this review, we first introduce commonly used photo-crosslinkable hydrogel materials and additives (such as nanomaterials, functional cells, and drugs/cytokine), and then discuss the applications of the 3D bioprinted photo-crosslinkable hydrogel scaffolds for bone and cartilage engineering. Finally, we conclude the review with future perspectives about the development of 3D bioprinting photo-crosslinkable hydrogels in bone and cartilage engineering.

Indexed as

Bone and cartilage engineeringHydrogelPhoto-crosslinkingThree-dimensional printing

Identifiers

PMID34286152
PMCPMC8287509
OpenAlexW3185423606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.