Evidence map›Paper›PMID 34286147›Full record

ArticleInternational journal of bioprinting2021

Graphene Oxide-Embedded Extracellular Matrix-Derived Hydrogel as a Multiresponsive Platform for 3D Bioprinting Applications.

Laura Rueda-Gensini, Julian A Serna, Javier Cifuentes, Juan C Cruz, Carolina Muñoz-Camargo

Open access · diamondAbstract read
In one paragraph

Article in International journal of bioprinting, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Laura Rueda-GensiniDepartment of Biomedical Engineering, Universidad de Los Andes, Bogotá, 11171, Colombia.
Julian A SernaDepartment of Biomedical Engineering, Universidad de Los Andes, Bogotá, 11171, Colombia.
Javier CifuentesDepartment of Biomedical Engineering, Universidad de Los Andes, Bogotá, 11171, Colombia.
Juan C CruzDepartment of Biomedical Engineering, Universidad de Los Andes, Bogotá, 11171, Colombia.
Carolina Muñoz-CamargoDepartment of Biomedical Engineering, Universidad de Los Andes, Bogotá, 11171, Colombia.
Universidad de Los Andes · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decellularized extracellular matrices (dECMs) have shown enormous potential for the biofabrication of tissues due to their biomimetic properties that promote enhanced cellular interaction and tissue regeneration. However, biofabrication schemes requiring electrostimulation pose an additional constraint due to the insulating properties of natural materials. Here, we propose a methacryloyl-modified decellularized small intestine submucosa (SISMA) hydrogel, embedded with graphene oxide (GO) nanosheets, for extrusion-based 3D bioprinting applications that require electrostimulation. Methacryloyl biochemical modification is performed to enhance the mechanical stability of dECM constructs by mediating photo-crosslinking reactions, and a multistep fabrication scheme is proposed to harness the bioactive and hydrophilic properties of GO and electroconductive properties of reduced GO. For this, GO was initially dispersed in SISMA hydrogels by exploiting its hydrophilicity and protein adsorption capabilities, and

Indexed as

Electroconductive hydrogelExtracellular matrix bioinkGraphene oxidePhotocrosslinkingReduced graphene oxide

Identifiers

PMID34286147
PMCPMC8287511
OpenAlexW3160233617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.