Evidence map›Paper›PMID 34285959›Full record

ArticleInternational journal of particle therapy2021

Methodologies to Increase the Level of Evidence of Real-life Proton Therapy in Head and Neck Tumors.

Francesco Dionisi, Lamberto Widesott, Marco Van Vulpen, Clifton David Fuller, Rocco Frondizi, Marco Meneguzzo, Pierre Blanchard, Maurizio Amichetti, Giuseppe Sanguineti

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of particle therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Francesco DionisiProton Therapy Unit, Department of Oncology, Azienda Provinciale per I Servizi Sanitari (APSS), Trento, Italy.
Lamberto WidesottProton Therapy Unit, Department of Oncology, Azienda Provinciale per I Servizi Sanitari (APSS), Trento, Italy.
Marco Van VulpenProton Therapy Center, Delft, the Netherlands.
Clifton David FullerDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Rocco FrondiziDepartment of Management and Law, Tor Vergata University of Rome, Rome, Italy.
Marco MeneguzzoDepartment of Management and Law, Tor Vergata University of Rome, Rome, Italy.
Pierre BlanchardDepartment of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France.
Maurizio AmichettiProton Therapy Unit, Department of Oncology, Azienda Provinciale per I Servizi Sanitari (APSS), Trento, Italy.
Giuseppe SanguinetiDepartment of Radiation Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITProvincia Autonoma di Trento · ITUniversity of Rome Tor Vergata · ITInstitut Gustave Roussy · FRThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aims to present and assess available and new methodologies to increase the clinical evidence of proton therapy data for patients with head and neck cancer. Despite the increasing number of scientific reports showing the feasibility and effectiveness of proton therapy in head and neck cancer, clinical evidence on the potential benefits of its use remains low for several reasons. In this article, the pros and cons of consolidated and new methodologies in this setting such as randomized clinical trials, the model-based approach, and the use of prospective multicentric registries will be detailed.

Indexed as

head and neck cancermodel-based approachproton therapyrandomized trialsregistries

Identifiers

PMID34285959
PMCPMC8270108
OpenAlexW3174165449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.